Microbiology Flashcards

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1
Q

Staphylococcus

A

Gram positive cocci in clusters

Aerobic and facultative anaerobes.

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2
Q

Name the two important types of staphylococcus

A

Staph aureus

Coagulase negative staph

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3
Q

What differs staph aureus from other staphylococci?

A

On coagulase testing- staph aureus stains golden (only one that is coagulase +ve) whereas coagulase negative staph stay white.

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4
Q

Staph aureus

A

Common human pathogen
Produces enzymes (including coagulase)
Causes wound, bone, skin and joint infections
Some strains produce toxins

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5
Q

Give examples of toxins produced by staph aureus

A

Enterotoxin- food poisoning
SSSST- staph scalded skin syndrome toxin
PVL- panton Valentine leukocidin

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6
Q

Coagulase negative staph

A

Skin commensals

May cause infection in association with implanted artificial material e.g. heart valves.

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7
Q

Staph saprophyticus

A

Causes urinary tract infections.

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8
Q

Streptococcus

A

Gram positive cocci in chains

Aerobic and facultative anaerobes.

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9
Q

How are streptococci classified?

A

Haemolysis
Alpha haemolysis- partial heamolysis- kind of green looking
Beta haemolysis- complete haemolysis- obvious yellowy white
Gamma haemolysis- no change (no haemolysis)

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10
Q

Beta haemolytic streptococci

A

Pathogenic organisms

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11
Q

What toxin is produced by beta haemolytic streptococci?

A

Haemolysin- one of the many toxins produced. Can damage tissues.

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12
Q

How are beta haemolytic streptococci further classified?

A

Antigenic structure on surface (serological grouping)

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13
Q

Group A beta haemolytic strep cause which types of infections.

A

Throat, severe skin infections

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14
Q

Group B beta haemolytic strep cause which types of infections

A

Meningitis in neonates.

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15
Q

Alpha haemolytic streptococci

A

There are 2 important catergories- strep pneumoniae (commonest cause of pneumonia) and strep viridans (commensal of mouth, throat and vagina)

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16
Q

Non (gamma) haemolytic streptococci

A

Enterococcus species

Commensals of bowel and are a common cause of UTI

17
Q

How is the skin adapted to protect against infection?

A

Intact skin is less likely to become infected
Surface is dry
Sebum- fatty acids which inhibit bacterial growth
Competitive bacterial flora
Concept of resident and transient flora

18
Q

Competitive bacterial flora

A

Staphylococcus epidermis
Corynebacterium (diptheroids)
Proprionobacterium sp.