Microbiology 14 - Respiratory Tract Infection Flashcards

1
Q

What pattern of pneumonia is usually produced by streptococcus pneumoniae?

A

Neatly lobar pneumonia

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2
Q

What pattern of haemolyisis does S. pneumonia show?

A

Alpha haemolysis

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3
Q

What are the top 2 organisms that can cause CAP?

A

S. pneumoniae

H. influenzae

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4
Q

What are the 3 most likely organisms to cause CAP in neonates?

A

E coli
Group B strep
Listeria

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5
Q

What are the 3 most likely organisms to cause CAP in 1-6 month olds?

A

Chlamydia
S. aureus
RSV

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6
Q

What are the 2 most likely organisms to cause CAP in 6 month - 5 year olds?

A

Mycoplasma

Influenza

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7
Q

Recall the CURB 65 criteria

A
Confusion 
Urea > 7
Resp rate > 30
BP <90 systolic/ <60 diastolic
Age > 65
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8
Q

How will a CXR appear in bronchitis?

A

Normal

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9
Q

How should bronchitis be managed?

A

Bronchodilators and antibiotics IF bacterial cause (usually viral)

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10
Q

In which patient group is H. influenzae most likely to cause CAP?

A

Those with a pre-existing lung condition

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11
Q

Which cause of CAP is associated with confusion?

A

Legionella

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12
Q

What are the typical symptoms and signs of legionella pneumonia?

A

Confusion
Abdominal pain
Diarrhoea
Hyponatraemia

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13
Q

Why are penicillins ineffective in atypical pneumonia?

A

Organisms that can cause atypical pneumonia don’t have a cell wall

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14
Q

What are the possible extrapulmonary features of atypical pneumonia?

A

Hepatitis

Hyponatraemia

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15
Q

What is the biggest risk factor for coxiella burnetti pneumonia?

A

Exposure to domestic/ farm animals

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16
Q

How is coxiella pneumonia diagnosed?

17
Q

Which type of atypial pneumonia is spread by birds?

A

Chlamydia psittaci

18
Q

What imaging is needed to diagnose empyema?

19
Q

How can empyema be treated?

A

Large chest drain

20
Q

Which type of pneumonia might cause a mild anaemia?

A

M. tuberculosis

21
Q

What is a hospital-acquired pneumonia?

A

Pneumonia that develops within 48 hours of being in hospital

22
Q

How can upper and lower respiratory flora be identified and distinguished in HAP?

A

Bronchial lavage

23
Q

Which organism is the most common cause of HAP?

A

Enterobactericiae

24
Q

What is the typical CXR appearance of PCP pneumonia?

25
What antibiotic is used to treat PCP pneumonia?
Co-trimoxazole
26
Which patient population is most at-risk of aspergillus pneumonia?
Immunosuppressed (eg prolonged chemo/ HIV)
27
What is the treatment for aspergillus pneumonia?
Amphotericin B
28
Which 2 pneumonia-causing organisms can be tested for in urine?
S. pneumoniae Legionella NOTE: only useful in PAIRED samples
29
What is the antibiotic of choice to treat MRSA pneumonia?
Vancomycin
30
What is the antibiotic of choice to treat pseudomonas pneumonia?
Piptazobactam
31
What are the 1st and 2nd line antibiotic therapies for HAP?
1st line: Ceftazidine/ciprofloxacin +/- vancomycin | 2nd line: Piptazobactam and vancomycin