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5th Oral Disease - Histology Practicals > Microbiology > Flashcards

Microbiology Flashcards

1
Q

If had patient w/ hx of XLA w/ swelling and pus exuding what should do?

A

Radiograph - presence foreign bodies
Drainage of pus
Swab of pus

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2
Q

What organisms expect to see from infection XLA socket?

A

Anaerobic infection:
Prevotella
Fusobacterium
Treponema

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3
Q

How manage pt w/ infected socket?

A

Drain abscess and debride

If unwell/ sign spreading infection - prescribe ab

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4
Q

Pt w/ dental abscess post XLA was prescribed metro why has this not worked?

A

Metro is also effective against anaerobes
Issues: ab resistance, acquired resistance, ab not sensitive to organism, pt compliance, no local measure used - ab can’t reach site

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5
Q

Pt presents w/ redness and crusting at corner of mouth and erythema in denture bearing area - what is most likely cause?

A

Fungal infection - angular chelitis

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6
Q

If patient presented with suspected fungal infection - how manage?

A 
Swab denture bearing area
Swab commissure of mouth
Blood test 
Oral rinse 
Swab of denture
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7
Q

What might see in blood test if pt has fungal infection?

A

Decreased iron, vit B

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8
Q

What is oral rinse?

A

Saline rinse - non-specific to infective organism

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9
Q

What must swab be?

A

Dampened in saline

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10
Q

How manage pt w/ fungal infection?

A

Remove predisposing factors
OHI/ denture hygiene
Antifungals - systemic/ topical

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11
Q

Likely organism of fungal infection?

A

Hyphae candida - often Candida albicans (dimorphic)

See c. glabrata/ staph aureus

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12
Q

Different between hyphae and yeast form?

A

Hyphae - long/pathogenic

Yeast - rounded

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13
Q

What antifungals are indicated?

A

Miconazole - c.albicnas/ staph aureus

Nystatin - c.glabrata

Fusidic acid - s.aurues/ c.glabrata

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14
Q

Have patient w/ fluctuant swelling in buccal sulcus adjacent to carious retained root - how would take specimen?

A

Aspirate - retains environment (important in anaerobic infection)
Select correct medium to prevent oxygen exposure - agar/ reducing agent
FNA of pus - prevent contamination

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15
Q

Likely microbial infection in fluctuant swelling?

A

Mixed sample - anaerobes/ neutrophils

Black pigmenting anaerobes - prevotella/ porphymonas
Fusobacteria
Peptostreptococcus
Strep. viridian (caries)

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16
Q

How manage fluctuant swelling?

A

Local measures
XLA cause
Ab - systemic unwell/ spreading infection

17
Q

Ab for fluctuant swelling?

A

Penicillin - amoxilcillin

Metro if allergy

18
Q

What is abscess?

A

Pathological pus filled cavity

19
Q

What is common see on sample of actinomycosis?

A

Molar tooth colony - yellow granule (sulphur) -made of bacteria/ immune cells which become walled off

20
Q

What microbes responsible actinomycosis?

A

Actinomyces - a.isralei/ oris

Highly branched and filamentous organisms

21
Q

Histology of acinomycosis?

A

Slows growing lesion - forms necrotic lesions - granular material walled off w/ immune cells

22
Q

What need consider when prescribing for actinomycosis?

A

Length of course

Actinomyces are slow growing - 5 day course not enough - need 6-8 weeks minimum (amoxicillin)

23
Q

What to be wary of with broad spec ab?

A

GI upset - risk of C.difficile

24
Q

What is dx if pt has been loosing weight and presents w/ peusdomembranous yeast infection and corrugated vertical white striations on lat border of tongue?

A

Oral presentation of HIV

Candidosis infection
Oral hairy leukoplakia

25
Q

What is oral hairy leukoplakia associated w/?

A

EBV

26
Q

Typical presentation oral thrush?

A

Creamy plaques which rub off giving a bleeding base

27
Q

Organism responsible for oral thursh?

A

Candida albicans

28
Q

How tx pt w/ thrush?

A

Tx candida - topical/ systemic antifungals

29
Q

How manage pt if suspect oral manifestation HIV?

A

Refer GP - underlying immunosuppression/ HIV

30
Q

Issue w/ prevotella infections?

A

high resistance to ab - esp penicillin (prevotella - beta lactamase)

31
Q

What is macrolide?

A

-Mycin

Erythromycin etc.

5th Oral Disease - Histology Practicals (8 decks)

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