Bone Lesions Flashcards
What is compact bone?
Lamellar bone - dense
What is cancellous bone?
Lamellar bone with large marrow space
What is osteoblast?
Cells form bone
What is osteoclast?
Cells that resorb bone
What would expect see histology of XLA socket?
Granulation tissue
Woven bone at base of socket
What condition has characteristic orange peel appearance?
Fibrous dysplasia
What different types of fibrous dysplasia?
Monostotic
Polystotic - McCune Albright
Development fibrous dysplasia?
Developmental disorder due mutation GNAS1
Histology of fibrous dysplasia?
Chinese characters
Fine and branching trabecular of woven bone intervene within fibrous tissue
Management of FD?
Typically growth will stablaise
Can debulk/ decontour - after growth
Differential of radiolucency lower anterior - look like PAP?
Central giant cell lesion
Brown tumour hyperparathyroidism
Lateral periodontal cyst - between vital teeth
Odontogenic tumour
What see histology giant cell lesion?
Bone replaced by fibrous-vascular stroma
Lots large multi-nucleated cells
What lesions present same as giant cell lesion on histology?
Central/peripheral giant cell lesion
Cherubism
Hyperparathyroidism
How differentiate lesions appear same on histology?
Clinica info
Blood - hyperparathyroidsm (elevated PTH/ Ca)
