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5th Oral Disease - Histology Practicals > Benign Swellings > Flashcards

Benign Swellings Flashcards

1
Q

What is acanthosis?

A

Increase layer of prickle cell

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2
Q

What is epithelial atrophy?

A

Reduction in thickness epithelium

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3
Q

What is often seen in epithelial atrophy?

A

Loss of rete ridges

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4
Q

What is hyperkeratosis?

A

Increase thickness of normal keratin - at site usually keratinised

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5
Q

What is keratosis?

A

Keratinisation of non-keratisied epithelium

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6
Q

What is epithelial hyperplasia?

A

Increase thickness of epithelium thickness

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7
Q

What is granulation tissue?

A

Fibrous tissue - fibroblasts and endothelial cells

Occur in response to trauma

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8
Q

What do fibroblast cells look like in granulation tissue?

A

Spindle cells

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9
Q

Role of fibroblasts in granulation tissue?

A

Lay down collagen?

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10
Q

What tissue expect to see in pyogenic granuloma histologically?

A

Granulation tissue
Fibroblasts/ endothelial cells
May see inflammatory cells

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11
Q

What features would see histologically pyogenic granuloma?

A

Granulation tissue

May ulcerated surface w/ fibrous-purulent slough

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12
Q

Cause of pyogenic granuloma?

A

Trauma or irritation (e.g plaque/ denture/ ortho appliance)

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13
Q

What can predispose people to pyogenic granuloma?

A

Hormonal exacerbation

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14
Q

What is the management of pyogenic granuloma?

A

Excision - care in preganncy

Removal cause - e.g increased OH

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15
Q

What is the predominant tissue in fibrous epulis?

A

Fibrous connective tissue

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16
Q

Causes fibrous epulis?

A

Trauma/ irritation

17
Q

Management fibrous epulis?

A

Excision and removal of cause

18
Q

Where in mouth expect to see giant cell lesion?

A

Usually anterior

19
Q

What histologically would indicated giant cell lesion?

A

Multi-nucleated giant cells

Expect see vascular tissue w/ haemorrhage

20
Q

What need to exclude if histologically dx giant cell lesion?

A

If peripheral or central

21
Q

How exclude central giant cell lesions?

A

PA/ radiographs - if lesion in bone

Blood test

22
Q

What condition can appear to be associated with central giant cell lesions?

A

Hyperparathyroidism - increase PTH can cause similar histology

23
Q

How would squamous cell papilloma look?

A

White cauliflower like growth - well defined

24
Q

What expect if see multiple cauliflower looking growths?

A

Possible immuno-suppressions e/g HIV

25
Q

How dose histological appearance papilloma contribute clinical appearance?

A

Increase hyper-keratinised tissue - white appearance

Folded projections = cauliflower like appearnace

26
Q

What is cause of squamous cell papilloma?

A

HPV

6 or 11 - non-oncogenic

27
Q

Which HPV is oncogenic?

A

16/18

28
Q

Manage squamous cell papilloma?

A

Excision of margins and reassure

5th Oral Disease - Histology Practicals (8 decks)

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