Microbiology Flashcards

1
Q

Definition of pathogen.

A

Organism that causes or is capable of causing disease.

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2
Q

Definition of commensal.

A

Organism which colonies the host but causes no disease in normal circumstance.

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3
Q

Definition of opportunist pathogen.

A

Microbe that only causes disease if host defences are compromised.

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4
Q

Definition of pathogenicity.

A

The degree to which a given organism is pathogen/ any strategy to achieve this.

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5
Q

What colour does gram positive bacteria stain?

A

Purple.

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6
Q

What colour does gram negative bacteria stain?

A

Pink.

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7
Q

What acid-fast bacilli stains red with Ziehl-Neelsen Stain?

A

Mycobacteria e.g. TB.

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8
Q

What test is used to differentiate between staphylococci and streptococci?

A

Catalase test.

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9
Q

Is staphylococci positive or negative?

A

Positive.

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10
Q

Is streptococci positive or negative?

A

Negative.

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11
Q

What test is used to differentiate between staphylococcus aureus and staphylococcus. epidermis?

A

Coagulase test.

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12
Q

Characteristics of staphylococcus. aureus?

A
  • Gram positive, B-haemolytic cocci in clusters.
  • Skin infections, endocarditis, TSS and rapid onset food poisoning.
  • MRSA.
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13
Q

Characteristics of staphylococcus. epidermis?

A
  • Gram positive cocci in clusters.

- Infects prosthetic devices.

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14
Q

What are the three types of worms (helminths)?

A

Nematodes, Cestodes and Trematodes.

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15
Q

Define the pre-patent period?

A

The interval between acquiring infection and the appearance of eggs/larvae in the stool.

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16
Q

What are the two types of Hookworm?

A

Ancylostoma duodenale. and necator americanus.

17
Q

What are the five major groups of protozoa?

A

Flagellate, amoeba, microsporidia, sporozo and cilliat.

18
Q

Define selective toxicity and the treatment of fungal disease.

A

Antimicrobial drug therapy is to achieve inhibitory levels of agents at the site of the infection without host cell toxicity.

19
Q

What are the three classes of drugs used in the treatment of fungal diseases?

A

Polyenes, allylamines, echinocandins and azoles.