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PRINCIPLES REV > Microbio Concise > Flashcards

Microbio Concise Flashcards

1
Q

How does bacteria replicatiate

A

Binary fission

  • aerobic
  • microaerophilic
  • anaerobic
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2
Q

Pathogen

A

Harmful organism which produces a pathology

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3
Q

Commensal

A

Part of the normal flora

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4
Q

Opportunistic pathogen

A

Causes problems in the immunocompromised

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5
Q

Contaminant

A

Grows in culture accidentally

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6
Q

Pathogenicity

A

Ability of an organism to cause disease/ infection

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7
Q

Virulence

A

Degree/ severity of pathogenicity

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8
Q

Use of coagulase test

A

Differentiate between coag +ve (Staph. Aureus) and coag -ve (staphylococcus species eg staph epidermis)

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9
Q

What causes partial haemolysis?

A

Enzymes denaturing Hb in RBC

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10
Q

What causes complete haemolysis?

A

Enzymes lyse RBC

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11
Q

Commonest cause of bacterial meningitis

A

Neisseria Meningitidis

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12
Q

Bactericidal

A

Kills bacteria

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13
Q

Bacteriostatic

A

Inhibit bacterial growth

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14
Q

Examples of cell wall antibiotics

A

Penicillin, glycopeptides, cephalosporins

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15
Q

Examples of antibiotics which affect protein synthesis?

A

Macrolides, tetracyclines, aminoglyosides

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16
Q

Examples of antibiotics which affect DNA

A

Metronidazole, fluroquinolines, trimethoprim

17
Q

4 C’s to avoid due to increased C. dif risk

A

Cephalosporins
Co-amoxiclav
Ciprofloxacin
Clindamycin

18
Q

Causes of bacterial resistance

A

Genetic mutations
- transformation, conjugation, transduction
Overprescribing

19
Q

Viral replication

A
  • attachment
  • entry
  • uncoating
  • nucleic acid and protein synthesis
  • assembly
  • release

PRINCIPLES REV (8 decks)

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