Microbes in Oral Health and Disease Flashcards

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1
Q

What does ‘commensalism’ mean?

A

An association between 2 organisms in which one benefits and the other neither receives any benefit nor harm

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2
Q

Which category do most bacteria in our oral cavity fall under?

A

Commensals

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3
Q

What does ‘parasitism’ mean?

A

A symbiotic relationship in which one organism benefits, causing the other organism harm in doing so

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4
Q

What does ‘mutualism’ mean?

A

A symbiotic relationship in which both organisms involved receive mutual benefit

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5
Q

Which factors lead to a healthy host?

A
  • Immune system
  • Vaccines
  • Antimicrobial agents
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6
Q

Which factors lead to disease in the host?

A
  • Immuno-suppression
  • Virulence factors
  • Resistance
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7
Q

What are the contributors to oral health?

A
  • Integrity of oral mucosa
  • Lymphoid tissue
  • Saliva
  • Gingival crevicular fluid (GCF)
  • Humoral and cellular immunity
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8
Q

What is flagella used for?

A

Motility

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9
Q

What are pili used for?

A

Adhesion

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10
Q

What is the predominant immunoglobulin present in saliva and what does it do?

A
  • IgA

- Prevents microbial adherence to host surfaces

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11
Q

What is lysozyme and what does it do?

A

A bactericidal enzyme present in saliva that breaks down components in bacterial cell wall

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12
Q

How many microorganisms are present per ml of saliva?

A

10^8

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13
Q

Name 3 species of bacteria that are involved in dental caries

A
  1. Streptococcus mutans
  2. Lactobacillus species
  3. Actinomyces species
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14
Q

Which 4 factors must be present for caries to develop?

A
  1. Susceptible tooth surface
  2. Sugar
  3. Time
  4. Plaque bacteria
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15
Q

What does periodontal disease affect?

A
  • Supporting structures of the teeth: gingiva, periodontal ligament, alveolar bone
  • Chronic long lasting inflammation
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16
Q

What is marginal gingivitis?

A

Inflammation around gumline

17
Q

What is hyperplastic gingivitis?

A
  • Gingivitis that persists for a long time and is characterised by the proliferation of fibrous connective tissue causing enlarged firm gums
  • Also called proliferative gingivitis
18
Q

What is hyperplastic gingivitis also known as?

A

Proliferative gingivitis

19
Q

What are the features of advanced periodontal disease?

A

Detatchment of the periodontal ligament alveolar bone loss and eventual tooth loss

20
Q

What does ‘purulent’ mean?

A

Consisting of, containing or discharging pus

21
Q

What are the features of purulent infections in the oral cavity?

A
  • Pus forming
  • Formation of an abscess
    Intra/extra-oral swelling
22
Q

How can pseudomembranous candidiasis be treated?

A
  • Scraping it off

- Treated with anti fungal drugs

23
Q

What is candidal leukoplakia?

A
  • Variant of oral candidiasis
  • White patches that cannot be scraped off
  • Organism has grown into the membrane
  • Associated with premalignancy
24
Q

Which bacterial/fungal species cause angular cheilitits?

A

Candida species or staphylococcus aureus

25
Q

What can cause denture stomatitis?

A

Denture-wearers not cleaning their dentures properly/keeping them on all the time and never removing them and cleaning them

26
Q

What is a risk factor for candidal leukoplakia?

A

Smoking