Microbes as Weapons (Part 2) Flashcards

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1
Q

what has made it possible for smallpox to be eradicated from the world?

A

only has human hosts

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2
Q

incubation period: 7-17 days

A

smallpox

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3
Q

incubation period of smallpox

A

7-17 days

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4
Q

symptoms of smallpox

A

high fever, aches; rash appears on mucosa of mouth, spreads to arms and then trunk

rash becomes vesicular and then pustular; crusts then form.

30% mortality due to severe immune resonse from viremia

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5
Q

transmission: respiratory droplets, contact, airborne

A

small pox

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6
Q

how is smallpox transmitted?

A

droplets, contact, airborne (active for 2 days)

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7
Q

symptoms: high fever, aches

A

smallpox

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8
Q

symptoms: rash appears on mucosa of the mouth, spreads to arms and then trunk

A

smallpox

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9
Q

how to prevent the spread of smallpox?

A

isolation

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10
Q

therapy: none, supportive care only

A

smallpox

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11
Q

smallpox therapy

A

none, supportive care only

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12
Q

smallpox cure

A

no cure!

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13
Q

smallpox vaccine

A

stockpiled

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14
Q

smallpox treatment

A

no treatment!

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15
Q

no cure, no treatment, no therapy

A

smallpox

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16
Q

what type of vaccine is the smallpox vaccine?

A

live attenuated

17
Q

vaccine effective post-exposure if given within 4 days. what disease and why?

A

smallpox, because of the long incubation period

18
Q

characteristics of Yersinia pestis

A

gram negative rod
can look like a safety pin

19
Q

transmission of bubonic plague

A

NOT PERSON TO PERSON

flea transmits Y. pestis to a human

bacterium is carried to a lymph

bubo develops within days

Y. pestis begins interfering with the immune response

multiplying bacteria spill into bloodstream (septicemic plague), endotoxin –> shock

20
Q

how to treat bubonic plague?

A

antibiotics

21
Q

pneumonic plague transmission

A

person to person

transmitted Y pestis full “armed”

22
Q

fatality rate of bubonic plague?

A

50-75%

23
Q

fatality rate of pneumonic plague

A

approx. 100%

24
Q

how to prevent pneumonic plague

A

no vaccine

post-exposure prophylactic antibiotic therapy