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Microbiology Unit 4 > Meningitis Comparison Chart > Flashcards

Meningitis Comparison Chart Flashcards

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1
Q

what are the four types of meningitis that we studied in class?

A

Pneumococcal meningitis
Meningococcal meningitis
HiB meningitis
Neonatal meningitis

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2
Q

what is the causative pathogen of Pneumococcal meningitis?

A

Streptococcus pneumoniae

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3
Q

what is the causative pathogen of Meningococcal meningitis

A

Neisseria meningitides

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4
Q

what is the causative pathogen of HiB meningitis

A

Hemophilus influenzae

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5
Q

what is the causative pathogen of Neonatal meningitis

A

Streptococcus agalactiae and E. coli

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6
Q

virulence factors of Pneumococcal meningitis?

A

Capsule (prevents C3b deposition and aids attachment)

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7
Q

virulence factors of Meningococcal meningitis?

A

Capsule (prevents C3b deposition and aids attachment)
Endotoxin

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8
Q

virulence factors of HiB meningitis

A

Capsule

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9
Q

virulence factors of Neonatal meningitis

A

N/A/

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10
Q

list two roles of capsule in virulence factors of meningitis

A
  • prevent C3b deposition
  • aid attachment
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11
Q

other organism features of Pneumococcal meningitis (4)

A
  • Gram+
  • diplococcus
  • alpha hemolytic
  • opportunist
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12
Q

other organism features of Meningococcal meningitis

A
  • Gram(-)
  • coccus
    -Gram(-) bacteria bleb their outer membrane, resulting in a massive inflammatory response in the CNS causing endotoxic shock
  • capillary damage due to shock causes rash
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13
Q

other organism features of HiB meningitis (1)

A

Gram negative rod

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14
Q

other organism features of Neonatal meningitis (3)

A
  • Bacitracin resistance
  • Strep
  • E. coli is GNR
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15
Q

disease features of Pneumococcal meningitis

A

primary infection destroys mucociliary escalator, or trauma that allows contact between the nasopharynx and the CNS can provide the opportunity

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16
Q

disease features of Meningococcal meningitis

A

symptoms are typical of meningitis along with a rash of purplish spots called petechiae

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17
Q

what is petechiae?

A

rash of purplish spots, found in Meningococcal meningitis infection

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18
Q

disease features of HiB meningitis

A

N/A

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19
Q

disease features of Neonatal meningitis

A

from mother during childbirth can cause infection in the infant

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20
Q

epidemiology of Pneumococcal meningitis

A

most common in adults

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21
Q

epidemiology of Meningococcal meningitis

A

commonly seen in crowded and stressed populations like college dormitories

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22
Q

epidemiology of HiB meningitis (2)

A

cause of meningitis in unvaccinated children <5 years

eradicated 99% by vaccination

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23
Q

epidemiology of Neonatal meningitis

A

premature of low birth weight infants are at risk

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24
Q

diagnosis of Pneumococcal meningitis (2)

A
  • symptoms
  • CSF test: physical appearance, gram stain, protein/glucose levels
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25
Q

diagnosis of Meningococcal meningitis

A

CSF tests + rash

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26
Q

diagnosis of HiB meningitis

A

CSF tests

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27
Q

diagnosis of Neonatal meningitis

A

bulging fontanelle of neonate plus spinal tap for CSF analysis

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28
Q

treatment for all types of meningitis

A

ANTIBIOTICS!

29
Q

prevention of Pneumococcal meningitis

A

Vaccine:
Capsular vaccine for adults
conjugate vaccine for kids due to weak T-independent response so capsule+protein conjugate is given

30
Q

what makes up the conjugate Pneumococcal meningitis vaccine?

A

capsule + protein conjugate

31
Q

what vaccine is given to kids with Pneumococcal meningitis? why?

A

conjugate vaccine. weak T-independent response.

32
Q

prevention of Meningococcal meningitis

A

capsular and conjugate vaccine

33
Q

prevention of HiB meningitis

A

HiB conjugate vaccine has eradicated most incidence

34
Q

prevention of Neonatal meningitis (2)

A
  • Test mom for presence of A. galactiae and antibiotics during birth.
  • Also monitor low birth weight // high risk infants.
35
Q

Pneumococcal meningitis
Meningococcal meningitis
HiB meningitis
Neonatal meningitis

A

what are the four types of meningitis that we studied in class?

36
Q

Streptococcus pneumoniae

A

what is the causative pathogen of Pneumococcal meningitis?

37
Q

Neisseria meningitides

A

what is the causative pathogen of Meningococcal meningitis

38
Q

Hemophilus influenzae

A

what is the causative pathogen of HiB meningitis

39
Q

Streptococcus agalactiae and E. coli

A

what is the causative pathogen of Neonatal meningitis

40
Q

Capsule (prevents C3b deposition and aids attachment)

A

virulence factors of Pneumococcal meningitis?

41
Q

Capsule (prevents C3b deposition and aids attachment)
Endotoxin

A

virulence factors of Meningococcal meningitis?

42
Q

Capsule

A

virulence factors of HiB meningitis

43
Q

N/A

A

disease features of HiB meningitis OR virulence factors of Neonatal meningitis

44
Q
  • prevent C3b deposition
  • aid attachment
A

list two roles of capsule in virulence factors of meningitis

45
Q
  • Gram+
  • diplococcus
  • alpha hemolytic
  • opportunist
A

other organism features of Pneumococcal meningitis (4)

46
Q
  • Gram(-)
  • coccus
    -Gram(-) bacteria bleb their outer membrane, resulting in a massive inflammatory response in the CNS causing endotoxic shock
  • capillary damage due to shock causes rash
A

other organism features of Meningococcal meningitis

47
Q

Gram negative rod

A

other organism features of HiB meningitis (1)

48
Q
  • Bacitracin resistance
  • Strep
  • E. coli is GNR
A

other organism features of Neonatal meningitis (3)

49
Q

primary infection destroys mucociliary escalator, or trauma that allows contact between the nasopharynx and the CNS can provide the opportunity

A

disease features of Pneumococcal meningitis

50
Q

symptoms are typical of meningitis along with a rash of purplish spots called petechiae

A

disease features of Meningococcal meningitis

51
Q

rash of purplish spots, found in Meningococcal meningitis infection

A

what is petechiae?

52
Q

N/A

A

disease features of HiB meningitis OR virulence factors of Neonatal meningitis

53
Q

from mother during childbirth can cause infection in the infant

A

disease features of Neonatal meningitis

54
Q

most common in adults

A

epidemiology of Pneumococcal meningitis

55
Q

commonly seen in crowded and stressed populations like college dormitories

A

epidemiology of Meningococcal meningitis

56
Q

cause of meningitis in unvaccinated children <5 years

eradicated 99% by vaccination

A

epidemiology of HiB meningitis (2)

57
Q

premature of low birth weight infants are at risk

A

epidemiology of Neonatal meningitis

58
Q
  • symptoms
  • CSF test: physical appearance, gram stain, protein/glucose levels
A

diagnosis of Pneumococcal meningitis (2)

59
Q

CSF tests + rash

A

diagnosis of Meningococcal meningitis

60
Q

CSF tests

A

diagnosis of HiB meningitis

61
Q

bulging fontanelle of neonate plus spinal tap for CSF analysis

A

diagnosis of Neonatal meningitis

62
Q

ANTIBIOTICS!

A

treatment for all types of meningitis

63
Q

Vaccine:
Capsular vaccine for adults
conjugate vaccine for kids due to weak T-independent response so capsule+protein conjugate is given

A

prevention of Pneumococcal meningitis

64
Q

capsule + protein conjugate

A

what makes up the conjugate Pneumococcal meningitis vaccine?

65
Q

conjugate vaccine. weak T-independent response.

A

what vaccine is given to kids with Pneumococcal meningitis? why?

66
Q

capsular and conjugate vaccine

A

prevention of Meningococcal meningitis

67
Q

HiB conjugate vaccine has eradicated most incidence

A

prevention of HiB meningitis

68
Q
  • Test mom for presence of A. galactiae and antibiotics during birth.
  • Also monitor low birth weight // high risk infants.
A

prevention of Neonatal meningitis (2)

Microbiology Unit 4 (19 decks)

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