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Microbiology Unit 4 > Meningitis Comparison Chart > Flashcards

Meningitis Comparison Chart Flashcards

1
Q

what are the four types of meningitis that we studied in class?

A

Pneumococcal meningitis
Meningococcal meningitis
HiB meningitis
Neonatal meningitis

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2
Q

what is the causative pathogen of Pneumococcal meningitis?

A

Streptococcus pneumoniae

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3
Q

what is the causative pathogen of Meningococcal meningitis

A

Neisseria meningitides

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4
Q

what is the causative pathogen of HiB meningitis

A

Hemophilus influenzae

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5
Q

what is the causative pathogen of Neonatal meningitis

A

Streptococcus agalactiae and E. coli

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6
Q

virulence factors of Pneumococcal meningitis?

A

Capsule (prevents C3b deposition and aids attachment)

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7
Q

virulence factors of Meningococcal meningitis?

A

Capsule (prevents C3b deposition and aids attachment)
Endotoxin

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8
Q

virulence factors of HiB meningitis

A

Capsule

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9
Q

virulence factors of Neonatal meningitis

A

N/A/

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10
Q

list two roles of capsule in virulence factors of meningitis

A
  • prevent C3b deposition
  • aid attachment
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11
Q

other organism features of Pneumococcal meningitis (4)

A
  • Gram+
  • diplococcus
  • alpha hemolytic
  • opportunist
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12
Q

other organism features of Meningococcal meningitis

A
  • Gram(-)
  • coccus
    -Gram(-) bacteria bleb their outer membrane, resulting in a massive inflammatory response in the CNS causing endotoxic shock
  • capillary damage due to shock causes rash
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13
Q

other organism features of HiB meningitis (1)

A

Gram negative rod

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14
Q

other organism features of Neonatal meningitis (3)

A
  • Bacitracin resistance
  • Strep
  • E. coli is GNR
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15
Q

disease features of Pneumococcal meningitis

A

primary infection destroys mucociliary escalator, or trauma that allows contact between the nasopharynx and the CNS can provide the opportunity

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16
Q

disease features of Meningococcal meningitis

A

symptoms are typical of meningitis along with a rash of purplish spots called petechiae

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17
Q

what is petechiae?

A

rash of purplish spots, found in Meningococcal meningitis infection

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18
Q

disease features of HiB meningitis

A

N/A

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19
Q

disease features of Neonatal meningitis

A

from mother during childbirth can cause infection in the infant

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20
Q

epidemiology of Pneumococcal meningitis

A

most common in adults

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21
Q

epidemiology of Meningococcal meningitis

A

commonly seen in crowded and stressed populations like college dormitories

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22
Q

epidemiology of HiB meningitis (2)

A

cause of meningitis in unvaccinated children <5 years

eradicated 99% by vaccination

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23
Q

epidemiology of Neonatal meningitis

A

premature of low birth weight infants are at risk

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24
Q

diagnosis of Pneumococcal meningitis (2)

A
  • symptoms
  • CSF test: physical appearance, gram stain, protein/glucose levels
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25
diagnosis of Meningococcal meningitis
CSF tests + rash
26
diagnosis of HiB meningitis
CSF tests
27
diagnosis of Neonatal meningitis
bulging fontanelle of neonate plus spinal tap for CSF analysis
28
treatment for all types of meningitis
ANTIBIOTICS!
29
prevention of Pneumococcal meningitis
Vaccine: Capsular vaccine for adults conjugate vaccine for kids due to weak T-independent response so capsule+protein conjugate is given
30
what makes up the conjugate Pneumococcal meningitis vaccine?
capsule + protein conjugate
31
what vaccine is given to kids with Pneumococcal meningitis? why?
conjugate vaccine. weak T-independent response.
32
prevention of Meningococcal meningitis
capsular and conjugate vaccine
33
prevention of HiB meningitis
HiB conjugate vaccine has eradicated most incidence
34
prevention of Neonatal meningitis (2)
- Test mom for presence of A. galactiae and antibiotics during birth. - Also monitor low birth weight // high risk infants.
35
Pneumococcal meningitis Meningococcal meningitis HiB meningitis Neonatal meningitis
what are the four types of meningitis that we studied in class?
36
Streptococcus pneumoniae
what is the causative pathogen of Pneumococcal meningitis?
37
Neisseria meningitides
what is the causative pathogen of Meningococcal meningitis
38
Hemophilus influenzae
what is the causative pathogen of HiB meningitis
39
Streptococcus agalactiae and E. coli
what is the causative pathogen of Neonatal meningitis
40
Capsule (prevents C3b deposition and aids attachment)
virulence factors of Pneumococcal meningitis?
41
Capsule (prevents C3b deposition and aids attachment) Endotoxin
virulence factors of Meningococcal meningitis?
42
Capsule
virulence factors of HiB meningitis
43
N/A
disease features of HiB meningitis OR virulence factors of Neonatal meningitis
44
- prevent C3b deposition - aid attachment
list two roles of capsule in virulence factors of meningitis
45
- Gram+ - diplococcus - alpha hemolytic - opportunist
other organism features of Pneumococcal meningitis (4)
46
- Gram(-) - coccus -Gram(-) bacteria bleb their outer membrane, resulting in a massive inflammatory response in the CNS causing endotoxic shock - capillary damage due to shock causes rash
other organism features of Meningococcal meningitis
47
Gram negative rod
other organism features of HiB meningitis (1)
48
- Bacitracin resistance - Strep - E. coli is GNR
other organism features of Neonatal meningitis (3)
49
primary infection destroys mucociliary escalator, or trauma that allows contact between the nasopharynx and the CNS can provide the opportunity
disease features of Pneumococcal meningitis
50
symptoms are typical of meningitis along with a rash of purplish spots called petechiae
disease features of Meningococcal meningitis
51
rash of purplish spots, found in Meningococcal meningitis infection
what is petechiae?
52
N/A
disease features of HiB meningitis OR virulence factors of Neonatal meningitis
53
from mother during childbirth can cause infection in the infant
disease features of Neonatal meningitis
54
most common in adults
epidemiology of Pneumococcal meningitis
55
commonly seen in crowded and stressed populations like college dormitories
epidemiology of Meningococcal meningitis
56
cause of meningitis in unvaccinated children <5 years eradicated 99% by vaccination
epidemiology of HiB meningitis (2)
57
premature of low birth weight infants are at risk
epidemiology of Neonatal meningitis
58
- symptoms - CSF test: physical appearance, gram stain, protein/glucose levels
diagnosis of Pneumococcal meningitis (2)
59
CSF tests + rash
diagnosis of Meningococcal meningitis
60
CSF tests
diagnosis of HiB meningitis
61
bulging fontanelle of neonate plus spinal tap for CSF analysis
diagnosis of Neonatal meningitis
62
ANTIBIOTICS!
treatment for all types of meningitis
63
Vaccine: Capsular vaccine for adults conjugate vaccine for kids due to weak T-independent response so capsule+protein conjugate is given
prevention of Pneumococcal meningitis
64
capsule + protein conjugate
what makes up the conjugate Pneumococcal meningitis vaccine?
65
conjugate vaccine. weak T-independent response.
what vaccine is given to kids with Pneumococcal meningitis? why?
66
capsular and conjugate vaccine
prevention of Meningococcal meningitis
67
HiB conjugate vaccine has eradicated most incidence
prevention of HiB meningitis
68
- Test mom for presence of A. galactiae and antibiotics during birth. - Also monitor low birth weight // high risk infants.
prevention of Neonatal meningitis (2)

Microbiology Unit 4 (19 decks)

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