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Microbiology Unit 4 > Digestive system infections (part 1) > Flashcards

Digestive system infections (part 1) Flashcards

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Biology 101 flashcards
1
Q

what is the method of pathogenesis of digestive infections?

A

first establish an intestinal infection and then spread systemically

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2
Q

what is the method of pathogenesis of cholera? (yellow box)

A

toxin production, lysogenic conversion!

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3
Q

what is the causative agent of cholera?

A

Vibrio cholerae

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4
Q

describe the characteristics of Vibrio cholerae

A

curved
gram - rod
polar flagellum
halotolerant
alkalophile
acid sensitive

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5
Q

curved

A

Vibrio cholerae

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6
Q

Gram negative

A

Vibrio cholerae; E. coli;

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7
Q

Rod

A

Vibrio cholerae; E. coli

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8
Q

Polar flagellum

A

Vibrio cholerae

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9
Q

Halotolerant

A

Vibrio cholerae

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10
Q

Alkalophile

A

Vibrio cholerae

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11
Q

Acid sensitive

A

Vibrio cholerae

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12
Q

symptoms of Cholera? (3)

A

rice water stools
abdominal cramping
severe dehyrdation

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13
Q

symptom: rice water stools

A

cholera

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14
Q

symptom: abdominal cramping

A

cholera

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15
Q

symptom: severe dehydration

A

cholera

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16
Q

how is cholera transmitted? (4)

A

contaminated water
contaminated food

fecal-oral is possible
person to person is not common

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17
Q

contaminated food = ? (cholera)

A

raw/undercooked seafood

rice, cereals, gruels left at ambient temperature

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18
Q

how to treat cholera?

A

immediate ORT or IV. hydration is the most important

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19
Q

how to prevent cholera?

A

sanitation and hygiene, avoid raw/uncooked food; bottled water, no ice, some countries offer vaccines

20
Q

what part of the body does cholera infect?

A

lower intestine

21
Q

a pathogenic sample is found in the lower intestine. where does it most likely come from?

A

ChoLera

chol is small

22
Q

in the name E. coli 0157:H7, what does the O represent?

A

O = LPS O antigen

23
Q

in the name E. coli 0157:H7, what does the H represent?

A

H = flagellar antigen

24
Q

lactose fermenter

A

E. coli

25
Q

a pathogenic sample is found in the large intestine. what is likely to have caused it?

A

E. coLi

L for large

26
Q

name some physical characteristics of E. coli (4)

A
  • gram negative rods
  • lactose fermenters
  • A/E lesions
  • toxin production
27
Q

digestive infection that produces A/E lesions

A

E. coli

28
Q

digestive infection that produces toxins

A

E. coli

29
Q

what is the treatment for E. coli?

A

there is no treatment! in fact, antibiotics make it worse

30
Q

what is the most important pathovar of E. coli?

A

STEC

31
Q

what does STEC stand for? what is it?

A

Shiga toxin producing E. coli

32
Q

how is the STEC toxin produced?

A

lysogenic conversion

33
Q

where in the body does E. coli / STEC colonize?

A

large intestine

34
Q

what effect does STEC have in the large intestine?

A

damage intestinal cells –> A/E lesions

35
Q

what are A/E/ lesions? what affect do they have in the body?

A

attaching and effacing. the damage intestinal cells which leads to diarrhea

36
Q

HUS is a result of?

A

Shiga toxin

37
Q

what condition can Shiga toxin cause ?

A

HUS

38
Q

symptoms of HUS

A

decreased urination
blood in urine
brusing
bleeding

39
Q

decreased urination, GNR, toxin production

A

HUS

40
Q

blood in urine, GNR, toxin production

A

HUS

41
Q

bruising, GNR, toxin production

A

HUS

42
Q

name the three virulence factors // mechanisms of pathogenesis of E. coli

A
  1. attachment via pili
  2. use T3SS to make A/E lesions and kill cells
  3. produce shiga toxin that damage blood vessels in kidneys
43
Q

a digestive infection that attaches via pili

A

E. coli

44
Q

a digestive infection that uses T3SS to make A/E lesions

A

E. coli

45
Q

a digestive infection that produces shiga toxin to damage blood vessels in kidneys

A

E. coli

Microbiology Unit 4 (19 decks)

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