Micro/Virology

Question 1

What are the two most common modes of acquiring a C.diff infection that produces a dangerous level of toxins?

Answer 1

Antibiotic use and fecal oral transmission

Question 2

Enterotoxin B (which is an exotoxin) in C. diff has what actions; is it more or less destructive than A?

Answer 2

Actin depolymerization, cytoskeleton destruction and is essential to virulence and stronger than exotoxin A.

Question 3

As a physician what some ways you can reduce C.diff spread?

Answer 3

Antibiotic stewardship, and wearing gloves

Question 4

Is C.diff normal microbiotic flora in the gut?

Answer 4

Yes for some.

Question 5

Which bacterial species can form endospores when in nutrient depleted environments?

Answer 5

Clostridium and Bacillus species. Gram +

Question 6

Astrovirus; describe it

Answer 6

Icosahedral, naked, +ssRNA linear

Shaped like a star, fecal oral transmission,
mild gastroenteritis self limited