Micro- Parasitic Infections Flashcards

1
Q

Where is trypansoma cruzi typically found? What disease does it cause?

A
  • in central and south america
  • american trypansomiasis (Chagas Disease)
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2
Q

How is trypanosoma transmitted?

A
  • by reduviid bugs
  • they bite you and poop out the parasite, you scratch the bite and introduce the parasite to your system.
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3
Q

What is the progression of Chagas disease?

A

Asymptomatic from the ouset, permanent damage is not notice until years later.

-fibrosis of the myocardium and purkinje fibers

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4
Q

What is the affect of Chagas disease (american trypanomiasis) on the heart?

A
  • enlargement of the heart
  • cardiac arrhythmias
  • heart failure
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5
Q

How does on acquire Taenia solium?

A

-by eating undercooked infected pork

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6
Q

Where are the larvae of taenia solium located? Where do they mature?

A
  • the larvae are located in muscle tissue
  • they mature in the intestine into mature tapeworm
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7
Q

How does T. solium eggs get back to the pork?

A

-human feces ingested by pigm contain eggs which hatch and travel through the pigs body to the muscle and blood

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8
Q

What is trichinella spiralis generally found in? Why is it dificult to treat?

A
  • Generally found in bear meat
  • hard to treat because it is normally not found until it has already penetrated striated muscle cells
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9
Q

What is trichinella spiralis?

A

Spiral shaped nematode found in almost all mammals

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10
Q

Why does trichinilla spiralis cause muscle pain?

A

-becuase it embeds in striated muscle

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11
Q

What is sarcocystis? (think about it)

A
  • Rare muscle parasite
  • causes muscle cysts in human muscle
  • undercooked meat
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12
Q

What is the amastigote stage of parasitic development?

A
  • intracellular lifecycle stage
  • no flagella or cilia
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13
Q

Describe the trypomastigotic stage of parasitic development.

A
  • in the blood
  • infective stage, characteristic of trypanosoma
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14
Q

What are the drugs benznidazole and nifurtimox used to treat?

A

-Chagas disease resulting from trypanosomiasis infection

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15
Q

What causes cysticerosis?

A

tapeworm larvae crossing the intestinal wall and embedding in human muscle

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16
Q

What is the primary source of Trichinella spiralis infection in humans?

A

-undercooked bear meat

17
Q

Describe the life cycle of Trchinella spiralis.

A
  • larvae ingested and taken up by small intestine
  • develop into adult worms and live in mucosa
  • eggs released into intestinal tissues
  • develop into larvae and enter blood–>penetrate striated muscle where they live and develop in a nurse cell
18
Q

What are the symptoms of Tichinellosis? What is the drug of choice?

A
  • fever, muscle pains, weakness, eosinophilia, and myocarditis
  • Albendazole and corticosteroids