Micro-organisms - Skildum Flashcards

1
Q

What is the tropism for EBOV?

A

NK cells, Monocytes, Macrophages, Neutrophils

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2
Q

What is the tropism for HHV 6 & 7, HTLV 1 & 2, HIV 1 & 2?

A

T-lymphocytes

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3
Q

What is the tropism for EBV and HHV-8 (KSHV)?

A

B-lymphocytes

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4
Q

What is the tropism for CMV?

A

Monocytes & Macrophages

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5
Q

What is the tropism for Parvovirus B19?

A

BFU-E & CFU-E

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6
Q

What is the tropism for CTFV?

A

BFU-E, CFU-E, Red blood cells

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7
Q

Traits of EBOV?

A

(-)ssRNA virus

-Helical, Enveloped

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8
Q

Traits of CTFV?

A

dsRNA virus, segmented

-Icosahedral, Non-enveloped

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9
Q

Traits of HTLV-1 & 2, HIV 1 & 2?

A

Retroviruses
ssRNA, (+)
-Enveloped, Icosahedral

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10
Q

Traits of Parvovirus B19?

A

ssDNA, Non-enveloped, Icosahedral

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11
Q

Traits of EBV, CMV, HHV-6 & 7, KSHV?

A

Herpesviridae, dsDNA

-Enveloped, Icosahedral

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12
Q

What virus is non-icosahedral shaped? What is its shape?

A
Ebola virus (EBOV) 
Helical/Complex
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13
Q

What two viruses are non-enveloped?

A

CTFV, Parvovirus B19

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14
Q

What four viruses have a dsDNA genome?

A

Cytomegalovirus (CMV- HHV-5), HHV-6 & 7, EBV (HHV-4), Kaposi Sarcoma herpes virus (KSHV, HHV-8)

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15
Q

What four viruses have a dsDNA genome?

A

Herpes viruses!

Cytomegalovirus (CMV- HHV-5), HHV-6 & 7, EBV (HHV-4), Kaposi Sarcoma herpes virus (KSHV, HHV-8)

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16
Q

What is the CTFV genome?

A

dsRNA, segmented

17
Q

What is the Parvovirus B19 genome?

A

ssDNA (pos. or neg.)

18
Q

What is the HTLV-1, HTLV-2, HIV-1 and HIV-2 genome?

A

ssRNA, positive

19
Q

What is the Ebola virus genome?

A

ssRNA negative

20
Q

What virus do you use multiple anti-retrovirals to treat?

A

HIV-1 and HIV-2

21
Q

What virus do you use chemotherapy and BMT to treat?

A

Human T lymphotrophic virus (HTLV-1, HTLV-2)

22
Q

What virus do you use chemotherapy and BMT to treat?

A

Human T lymphotrophic virus (HTLV-1, HTLV-2)

23
Q

What virus do you used Ganciclovir, Cidofir and foscarnet to treat?

A

Kaposi Sarcoma Herpes Virus (HHV-8)

24
Q

What viruses do you just use supportive treatment for?

A

Ebola, Parvo B19, EBV, CTFV

25
Q

What two viruses do you give ganciclovir for immunocompromised patients?

A

CMV (HHV-5), HHV 6 & 7

26
Q

What virus do you give cidofovir to immunocompromised patients?

A

HHV-6 & 7