Micro - General

Question 1

Co-amoxiclav constituents

Answer 1

Amoxicillin and clavulanic acid

Question 2

Tazocin constituents

Answer 2

Piperacillin
Tazobactam

Question 3

Coverage of beta lactams

Answer 3

Penicillin - gram +ve
Everything else - Broad spectrum, includes Gram -ve

Question 4

Coverage of cephalosporins

Answer 4

Early gens = E. coli
Later gens = Gram -ves

Question 5

Mechanism of resistance for MRSA

Answer 5

Codes for new transpeptidase (PBP) → altered target

Question 6

Mechanism of resistance for pneumococci

Answer 6

PBP mutation

Question 7

Co-trimoxazole constituents

Answer 7

trimethoprim
Sulfamethoxazole

Both folate antagonists

Question 8

Abx for staph. Aureus kin infection

Answer 8

Flucloxacillin

Question 9

Abx for beta-haemolytic strep pharyngitis

Answer 9

Benzylpenicillin

Question 10

Abx for mild and severe community acquire pneumonia

Answer 10

Mild = Amoxcillin
Severe = co-amoxiclav + clarithromycin

Question 11

Abx for hospital acquired pneumonia

Answer 11

Co-amoxiclav + gentamicin OR tazocin

Question 12

Abx for meningococcal meningitis

Answer 12

Ceftriaxone ± amoxicillin

Question 13

Abx for UTI

Answer 13

Cefalexin OR co-amoxiclav

Question 14

Abx for severe and neutropenic sepsis

Answer 14

Severe: Tazocin/ceftriaxone + metronidazole ± gentamicin
Neutropenic: tazocin + gentamicin

Question 15

Abx for clostridium colitis

Answer 15

Metronidazole
2nd line: vancomycin
Stop any cephs