Micro final Flashcards

1
Q

what infectious disease is caused by Yersinia pestis

A

The plague

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2
Q

What infrectious disease is caused by Coccidioides immitis

A

Valley fever

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3
Q

What infectious disease is caused by Naegleria fowleri

A

primary amebic meningoencephalitis (PAM)

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4
Q

what infectious disease is caused by Corynebacterium diphtheriae?

A

Diptheria

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5
Q

What infectious disease is caused by Mycoplasma genitalium

A

Mgen

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6
Q

A quality for an antimicrobial drug that means the drug selectively kills or inhibits the growth of microbial targets while causing minimal or no harm to the host

A

selective toxicity

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7
Q

what four antibiotics inhibit cell wall biosynthesis?

A
  1. Penicillin G
  2. Vancomycin
  3. Cephalosporin
  4. Bacitracin
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8
Q

What four antibiotics inhibit protein biosynthesis?

A
  1. streptomycin
  2. tetracycline
  3. chloramphenicol
  4. azithromycin
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9
Q

what is the one antibiotic that disrupts membranes?

A

Polymyxin B

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10
Q

What are the three antibiotics that inhibit nucleic acid synthesis?

A
  1. Rifampin
  2. Nitrofurantoin
  3. fluoroquinolones
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11
Q

What antibiotic disrupts metabolic pathways

A

sulfa drugs

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12
Q

what are the seven challenges any good pathogen must overcome to cause disease?

A
  1. find a reservoir between hosts
  2. use a mode of transmission to get to the new host
  3. Must adhere to the surface’s of the host’s tissues and colonize the new host
  4. Must invade the new host to get into the deeper tissues
  5. Must evade host’s immune responses to establish an infection
  6. Must actually cause a disease (multply and produce toxins)
  7. Exit the host and go to a new host or back to the reservoir
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13
Q

what is index case?

A

The first case

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14
Q

what is etiology?

A

the study of the cause of the disease

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15
Q

Common source epidemic

A

a single source for all individuals affected

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16
Q

Propagated spread

A

occurs from direct or indirect person to person contact - no single source for infection

17
Q

What are the three types of transmission used by pathogens to get to new hosts? Give examples of each type and know the subtypes of each type (if applicable).

A
  1. vector
  2. contact
  3. vehicle
18
Q

An epidemic that occurs on a worldwide scale

A

pandemic

19
Q

When a larger number than expected cases occur in a short time in a geographic area

A

epidemic

20
Q

when diseases that are constantly present in a population

A

endemic

21
Q

Proteins made by bacteria and secreted from cells. Are toxic in small doses but are not pyrogenic. Can be denatured with heat. Can be made by Gram - or Gram +

A

Exotoxins

22
Q

Made of lipopolysaccharides (LPS) which are actually part of the outer membranes of dead Gram - bacteria.
Can’t be denatured with heat (no vaccines are made with them)
They are pyrogenic
Are only toxin in large doses

A

endotoxins

23
Q

What is an example of a passive portal of exit?

A

through a sneeze or cough

24
Q

what is an example of an active portal of exit

A

oozing sores and ruptured vesicles

25
Q

who was the first person to grow organisms in a pure culture and invent agar based media?

A

Robert Koch