Micro 2 Flashcards

1
Q

GP Cocci

A

Staph

Strep

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

GP Rods

A
Actinomyces
Bacillus
Clostridium
Diptheria
Listeria
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

GN Cocci

A

Neisseria

Moraxella

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

GN Rods

A

Enterobacteria

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

GN Coccobacilli

A

Haemophilus
Bordatella
Pseudomonas
Chlamydia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

GN Spirochaetes

A

Treponema
Leptospira
Borrelia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Strep Subtypes

A

Beta Haemolytic, clear (Pyogenes, agalactae)
Gamma-Haemolytic
Alpha Haemolytic, green (Pneumoniae, viridans)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

HAP

A

Staph a
Klebs
Pseudomonas
haemophilus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Causes of typical pneumonia

A
Strep
Haemophilus
Moraxella
Staph a
Klebsiella
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Strep Pneumoniae

A

Rusty coloured sputum

Lobar

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Haemophilus pneumonia

A

smoking, copd

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

moraxella pneumonia

A

smoking

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

staph a pneumonia

A

post-influenza

Cavitation on cxr

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Klebsiella pneumonia

A

alcoholism
haemoptysis
elderly

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Atypical pneumonia causes

A

Legionella (Travel, air conditioning, low sodium, hepatitis)
Mycoplasma (Flu-like, schools/unis, AIHA cold agglutinins positive, erythema multiforme)
Chlamydia (birds)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

CURB 65

A
Confusion
Urea >7
Resp Rate >30
SBP <90
>65
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

CURB 65 0-1

A

Amox PO 5d outpatient

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

CURB 2

A

Amox + Clarithromycin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

CURB 3-5

A

Co-amox + Clarithromycin + admit

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Pott’s Disease

A

Spinal TB
Discitis
Back pain
Iliopsoas Abscess

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Milliary TB

A

Disseminated Haematogenous

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

TB Investigations

A

CXR
Ziehl Neelson Stain
Lowenstein-Jensen medium cultrue
Acid-fast bacilli

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

TB Exposure investigations

A

Tuberculin skin test (mantoux/heaf) for previous exposure

IGRA (elispot) for active/latent, but not bcg vaccine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

TB management

A
RIPE
Rifampicin 6m
Isoniazid 6m
Pyrazinamide 2m
Ethambutol 2m
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Non-TB mycobacterium
Leprosy (skin depigmentation, nodules, nerve thickening) Marinarum (fish) Ulcerans (Australia) Avium (immunocompromised)
26
Syndromes of GI infections
Secretory Diarrhoea Inflammatory Diarrhoea Enteric Fever
27
Secretory Diarrhoea
Toxins -> Cl in lumen -> loss of water/electrolytes No fever, watery Cholera, ETEC, EAggEC, EPEC, EHEC
28
Inflammatory Diarrhoea
Inflammation and Bacteraemia Fever, D sometimes bloody Campylobacter, Shigella, Salmonella, EIEC
29
Enteric Fever
Fever/unwell, fewer GI symptoms | Typhoid, Yersinia, Brucella
30
Bacillus Cereus
Vomiting after reheated Rice
31
S.Aureus GI
Vomiting and watery diarrhoea, spread by unwashed hands
32
Clostridium Botulinum
Descending Paralysis | Honey, Canned Foods
33
C. Perfringens
8-16h after reheated meart Gas Gangrene Watery Diarrhoea
34
Clostridum Difficile GI
Pseudomembranous Colitis post Abx | Cephalosporins, Ciprofloxacin, Clindamycin
35
Vibrio cholera
Rice water stool | Shellfish
36
Salmonella enteritides GI
Poultry and Eggs | Non-bloody diarrhoea
37
Shigella GI
Bloody Diarrhoea | MSM
38
Campylobacter GI
Poultry (BBQ) Bloody, foul-smelling Diarrhoea GBS Reactive Arthritis
39
E Coli GI
Toxin - ETEC (traveller's diarrhoea), EHEC ( Bloody Diarrhoea O157, Outbreaks) Inflammatory - EIEC, Bloody Diarrhoea
40
GI Viruses
Secretory DV Noro - Adult outbreaks, hospitals Rota - Children, oral vaccine Adeno - Infants
41
Fever in the returning traveller
Typhoid Dengue Malaria
42
Typhoid
Salmonella typhi/paratyphi India, food/water 1-2wks ago Constipation, Fever, headache, Rose spots on trunk, hsmegaly, bradycardia Peyer's Patch infection = GI Perforation
43
Typhoid Management
IV Ceftriaxone | PO Azithromycin
44
Dengue
Flavivirus by Ades Mosquito SEAsia, urban, days incubation Fever, myalgia, rash Mild, self-limiting
45
Dengue reinfection with different serotype?
Dengue Haemorrhagic Fever/Dengue Shock | Supportive
46
Malaria
Plasmodium spp. by F Anopheles Mosquito Falciparum = Severe Non-Falciparum = less severe Africa, Asia, South America
47
Malaria Presentation
``` Tertian Fever (48h) HSmegaly, Haemolytic Anaemia ```
48
Malaria Investigations
Thick and thin blood films Thick = malaria Thin = species
49
Malaria Management
Mild = Artemisin combo (riamet) = artemether + lumefantrine Severe - IV artesunate
50
Rabies
Rhabdovirus Encephalitis, hypersalivation, hydrophobia Negri Bodies Passive vaccination post exposure
51
Lyme Disease
Borellia burgoferi Ixodes Tick Flu/late neuro Sx Erythema chronicum migrans
52
Leptospirosis
``` Dog/rat urine Swimming COnjunctival Hameorrhage Jaundice Spiking Fever ```
53
QFever
Coxiella burnetii | Atypical Pneumonia, fever, dry cough, pleural effusion
54
UTI Causes
E Coli most common Staph. saprophyticus in young women Abnormal Tract? Proteus, Klebsiella Haematogenous? S.aureus
55
UTI MC&S results
>10^3 common organisms >10^4 others >10^7 WCC = sterile inflammation Mixed growth = contamination
56
UTI Management
Lower - Nitrofurantoin, trimpethroprim, cephalexin, amox 3d if uncomplicated, 7d if complicated Upper - Admit, IV co-amox + gentamycin
57
Chlamydia Subtypes
A-C - Trachoma D-K - STI, Opthalmia in neonates L1-3 - LGV
58
Chlamydia Investigations
Swab, NAAT
59
Chlamydia Management
Azithromycin | Doxyclycline
60
Gonorrhoea
Urethral Discharge in men NAAT/Culture Ceftriaxone
61
Primary Syphylis
Painless solitary ulcer (chancre) | 4-6wks
62
Secondary Syphylis
1-6m, Fever, Lymphadenopathy Rash on palms and soles Genital Warts
63
Latent Syphylis
Asymptomatic
64
Tertiary Syphylis
2-30y Gummatous: Skin/Bone/Mucosal Granulomas CV: Any CVS disease, aortic root dilatation Neurosyphylis: Dementia, Tabes dorsalis, Argyll-robertson pupil
65
Syphylis Investigations
Primary Lesion -> Dark Ground microscopy Non-treponemal tests: antibodies Common false positives Treponemal Test
66
Syphylis Treatment
IM Benzathine Penicillin
67
Meningitis Cauases
``` Neisseria, Strep. pneumonia Neonates - GBS, Listeria, E Coli Elderly - GBS, Listeria TB Enterovirus Cryptococcus ```
68
Bacterial Meningitis Lumbar Pucnture
Turbid Low Glucose High polymorphic WCs
69
Viral Meningitis Lumbar Puncture
Clear Normal Glucose High, mononuclear WCs
70
TB Meningitis Lumbar Puncture
Clear/Turbid Low Glucose High mononuclear WCs
71
Meningitis Management
IV Ceftriaxone + Corticosteroids Ampicillin if Listeria Suspected Acyclovir if altered consciousness
72
Infective Endocarditis location
Mitral/Aortic Valves Tricuspid in IVDU Changing heart murmur
73
Infective Endocarditis causes
Strep pyogenes, Staph a (IVDU) CoNS (prosthetic valves) Subacute -> Staph epidermis, Strep viridans
74
HACEK IE
``` Haemophilus Acinetobacter Cardiobacterium Eikinella Kingella ```
75
Subacute IE
``` Janeway Lesions Splinter Haemorrhages Splenomegaly Roth Spots Osler's Nodes ```
76
IE Investigations
3x cultures Echo Duke's Criteria (2mj, 1mj 3mn, 5mn)
77
Wound/Bone/Joint Infections
Staph. aureus | Flucloxacillin
78
Hospital Acquired Infections
>48h hospital admission | Pneumonia, Pseudomembranous COlitis, UTI, Bacteraemia
79
Pyrexia of unknown origin
>38.3 >3wks >1wk Intensive INvestigations
80
Pyrexia of unknown origin causes
``` Abscesses, IE, TB, HIV seroconversion, Atypical Malignancy Inflammation Drugs (transfusion, serotonergics) Surgery ```