MI Flashcards
Lad blocked
Anterior wall
Rca marginal
Medical wall
Circumflex
Lateral walls
Rca blocked
Posterior walls
Diagnosis of acute mi
Chest pressure Left arm Chest heaviness Radiation to jaw neck shoulder back arms Nausea Vomiting Dyspnea Lightheadedness Sweating Confusion
Syndromes
Stable angina
Unstable angina
Non St elevation mi
St elevation mi
Stable angina
Transient episodic chest discomfort
Predictable
Follows physical an emotional stress
Ecg: normal t-wave changes ST depression
Unstable angina
Rest/new onset angina
Worsening in severity with less provocation
Same as stable angina
ECG changes ischemia
Inverted t waves
St segment depression
ECG changes injury
S-t elevation
T wave inversion
ECG of infarct
Associated with q waves
Events leading to mi
Atherosclerosis Plaque ruptures Platelet aggregation Thrombus formation Vessel occlusion Vasospasm Distal ischemia
Irreversible injury requires ?
30 mins ischemia
Other characteristics of injury
Chronic O2 deficiency makes cells more resistant
After 30-60mins cell death starts
80% of cells at risk die within 3hrs
Almost 100% by 6hrs
Why increase level of cardiac enzymes
With death: Holes appear Small, cytoplasmic markers leak quickly Larger complex markers released slowly Direct relationship between concentration of these markers and size on infarct