Cardiac Function Flashcards

1
Q

Ejection fraction =

A

Sv / Edv

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2
Q

At rest ejection fraction

A

70%

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3
Q

Factors affecting cardiac output

A

Hr and stroke volume

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4
Q

Factors affecting stroke volume

A

Pre load and after load

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5
Q

Factors affecting preload

A

Venous return
Ventricular plasticity
Ventricular size

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6
Q

Factors affecting venous return

A

Pumps

Blood volume

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7
Q

Factors affecting after load

A

Contractility

Systemic vascular resistance

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8
Q

Factors affecting contractility

A

Myocardial mass
Length tension relationship
SNS
Adrenaline

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9
Q

Factors affecting HR

A

PNS
Sns
Adrenaline

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10
Q

Pns vs Sns

A
Pns = lower hr
Sns = increased hr and strength
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11
Q

Denervated heart rate

A

100

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12
Q

Normal hr

A

72 dominated by Pns

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13
Q

Pns potential

A

Decrease to 0

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14
Q

Sns potential

A

Increase by 300%

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15
Q

Pns nerve

A

Venus nerve

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16
Q

Sns nerve

A

Cardiac nerves

17
Q

Ventricular size

A

The bigger the lv the bigger the sv

18
Q

Ventricular plastisticity

A

Healthy myocardium stretches

Helps frank staling mechanism

19
Q

Limiting factor of plastisticity

A

Pericardium

20
Q

Frank staling mechanism

A

Increased stretching of myocardial walls will increase strength

21
Q

Cardiac muscle length tension relationship

A

Similar properties to skeletal muscle

Normally operates well below optimum length

22
Q

Ventricular volume on the lt relationship

A

Increased volume stretches the ventricular muscle towards optimum

Stretching the ventricles increases the pressure they can generate

23
Q

At rest where does the heart operate in rages to lt relationship

A

On the toe therefore increased filling immediately leads to increased q

24
Q

Blood volume in adults

A

5l

25
Q

Blood redistribution

A

At rest 20% to muscle

In exercise 85% to muscle

26
Q

Blood volume at rest

A

Excess blood 2/3 resides in veins

27
Q

Blood volume in exercise

A

Insufficient volume blood is shunted away from non workin muscle

28
Q

Vasodilator a

A
Nitric oxide increased
Bradykinin increase
Prostaglandins increase
Increased potassium 
Increased co2
Increased lactate
Decreased local po2
29
Q

Vasoconstriction.

A

Increased Sns activity releases NE

ACTS on alpha receptors in smooth muscle to cause constriction

30
Q

Venous return pumps

A

Ventricular
Ventricular rotation
Respiratory
Muscular

31
Q

Ventricular pump

A

High pressure durning contraction

Low pressure durning relaxation creates a vacuum sucking bloody towards heart

32
Q

Ventricular rotation

A

Wrings blood out in systole

Twists and recoils to suck blood in diastole

33
Q

Respiratory

A

Pressure Increases in thorax during expiration = blood towards heart

Pressure low during inspiration creates vacuum drawing blood towards heart

34
Q

After load and cardiac performance

A
Factors which impede ejection fraction
Volume of blood in arterial circulation 
Pressure in aorta 
Compliance of aorta
Size of pulmonary / aorta lumen
Inertial component of ejecting blood column
35
Q

After load and cardiac performance 2

A

Stroke volume down
Preload increased
Reduced velocity
Increased myocardial O2 consumption

36
Q

Stroke volume = ?

A

Preload - after load