MHC Flashcards

1
Q

Other name of MHC

A

human leukocyte antigen (HLA)

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2
Q

In humans these molecules are encoded by several genes all clustered in the same region on chromosome __

A

6

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3
Q

Class III MHC molecules code for

A

Complement proteins
Cytokines
Enzymes

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4
Q

TH cells recognize antigen combined with class ___ molecules, whereas TC cells generally recognize antigen combined with class __ molecules.

A

2, 1

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5
Q

Intracellular peptides for MHC class I presentation are made by ___in the cytosol, then transported into the endoplasmic reticulum via ___ to be further processed.

A

proteases and the proteasome , TAP (Transporter associated with Antigen Processing)

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