Application Of Vaccines

Question 1

MMR combo vaccine has been available since

Answer 1

2005

Question 2

Types of measles vaccines

Answer 2

1. Mumps Measles Rubella vaccine, live (MMR-II)
2. Mumps Measles Rubella and Varicella virus vaccine

Question 3

Dose schedule of MMR vaccine

Answer 3

First at 12 months
Second at age four to six years

Question 4

Two polio vaccines are used throughout the world to combat poliomyelitis:

Answer 4

Injected dose
Oral vaccine

Question 5

Three virulent strains on which IPV vaccine is based on:

Answer 5

1. Mahoney (type 1 poliovirus)
2. MEF 1 (type 2 poliovirus)
3. Saukett

(These are made through non-human cells)

Question 6

A single dose of oral polio vaccine contains

Answer 6

1. 1000000 units of Sabin 1 (effective against PV1)
2. 1000000 units of Sabin 2 strain
3. 600000 units of Sabin 3

Question 7

Dose schedule of polio vaccine

Answer 7

1. OPV at birth
2. OPV and IPV at 6, 10 and 14 weeks
3. OPV and IPV at 15-18 months
4. OPV at 5 years

Question 8

Two effective types of typhoid vaccines

Answer 8

1. Ty21a (live vaccine given orally)
2. Vi capsular polysaccharide vaccine, injectable subunit vaccine

Question 9

Dose schedule of typhoid vaccine

Answer 9

Boosters every 5 years
Vi capsular: 2 years and older (booster required every 3 year)

Question 10

In Pakistan there are estimated _ million carriers of HBV

Answer 10

7 to 9 million carriers

Question 11

HBV infection causes

Answer 11

1. Chronic hepatitis
2. Cirrhosis of liver
3. Hepatocellular carcinoma

Question 12

Solution to HBV

Answer 12

HBIG (hepatitis B immunoglobulin) provides passive immunity
+
Hep B vaccine

Question 13

Dose schedule HBV

Answer 13

Birth ,1 and 6 months
Birth, 6 and 14 weeks
6, 10 and 14 weeks

Question 14

Types of Tetanus Vaccines

Answer 14

1. DT or Td (in combination with diphtheria)
2. TT in wound management
3. TT in pregnancy

Question 15

Dose Schedule for tetanus

Answer 15

1. Unimmunized children ( 1 and 6 months)
2. Partially immunized: vaccine entails administration of at least 3 does of TT including previous doses

Question 16

Nanopatch has a specially designed surface having approximately

Answer 16

20,000 micro-projections per square centimetre

Question 17

___ represent an important advance in Vaccine technology

Answer 17

Vaxart’s oral vaccines

Question 18

Oral vaccine’s typically generate a large amount of

Answer 18

Secretory igA antibodies .. play a major role in mucosal defence