MFM

Question 1

TOCO
List the tocolytics and drug class

Answer 1

1) terbutaline - B2 agonist
2) magnesium Sulfate
3) Indomethacin - prostaglandin synthase inhibitor
4) Nifedipine - CCB

Question 2

TOCO
MOA of terbutaline

Answer 2

B2 agonist
Bind receptor ➡️ +adrenyl Cyclase➡️ATP➡️cAMP➡️decrease Ca+➡️decrease contraction

Question 3

TOCO
MOA of Mag Sulfate

Answer 3

1) Decrease Ach release at NMJ
2) Calcium agonist

(Causes resp depression, peristalsis, hypotension, hypotonia)

Question 4

TOCO
Nifefiping MOA

Answer 4

CCB ➡️⬇️ uterine contraction

(Can leas to uteroplacental insufficiency)

Question 5

TOCO
Terbutaline MOA

Answer 5

B-2 agonist ➡️myometrium and activates adrenyl Cyclase (ATP➡️cAMP).

Question 6

Fetal alcohol syndrome features (list 6)

Answer 6

SHORT palpebral fissures
THIN vermillion border
SMOOTH philtrum
MICROcephaly
SGA
Low IQ
(Everything is smaller/shorter/thinner)

Question 7

TTT Syndrome. Which type of twins are more affected and what are the stages.

Answer 7

Monochorionic Diamniotic
I) poli-Oli(donor)
II) absent bladder
III) doppler changes
IV) Hydrops (Recipient)
V) Demise

TOPS - Twin Oligo-Poly Sequence
TAPS - Twin Anemia-Polycy Sequence

Question 8

Diabetes: which causes more problems: type 1/2 or gestational?

Answer 8

Type 1/2 > gestational. Remember that HA1c >10 at conception = 25% risk of malformations (GDM women should have normal HA1c around conception)

Question 9

What does ponderal index determine with growth restriction

Answer 9

Low PE = asymmetric growth restriction