mevalonate pathway 1 Flashcards

1
Q

modified terpenes by oxygen added or methyl removed or moved

A

terpenoids

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2
Q

arise from acetate via mevalonic acid

A

isoprene

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3
Q

branched 5 carbon units with 2 unsaturated bonds

A

isoprene

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4
Q

isoprene is chemically known as

A

2 methyl 1,3 butadiene

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5
Q

class name for the 1 to 8 isoprene units

A
hemiterpene-1
monoterpene-2
sesquiterpene-3
diterpene-4
sesterterpene-5
triterpene-6
tetraterpene-8
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6
Q

natural products whose structures may be divided into isoprene units

A

terpenes

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7
Q

2 active isoprene units

A

DMAPP- dimethylallyl diphosphate

IPP- isopentyl diphosphate

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8
Q

2 pathways involved in biosynthesis of isoprene

A

mevalonate

methylerythritol phosphate

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9
Q

triterpenes comes from 2

A

sesquiterpenes

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10
Q

tetraterpenes comes from 2

A

diterpene

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11
Q

3 hemiterpenes

A

IPP
DMAPP
isoprene

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12
Q

alkylating agent for meroterpenoids

A

DMAPP

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13
Q

constitutes volatile oils and used as flavoring agents

A

monoterpenes

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14
Q

used as liniments against rheumatic pain

A

camphor

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15
Q

liniments and ointments against itching

A

menthol

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16
Q

used as an aromatic bitter tonic and remedy for poor appetite

A

bitter orange peel

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17
Q

monoterpenes used as bactericidal preparations

A

thymol and carvacrol

18
Q

isomers of geranyl PP

A

linalyl PP

neryl PP

19
Q

precursors for cyclic monoterpens biosynthesis

A

neryl PP

linalyl PP

20
Q

structural forms of monoterpenes

A

acyclic
monocyclic
bicyclic

21
Q

the acyclic monotepenes are

A

hydrocarbons
aldehydes
alcohols

22
Q

formation of menthane type monoterpenes

A

monocyclic monoterpenes

23
Q

fates of methyl/ alpha terpinyl carion in monocyclic monoterpens

A

quenching ith nucleophiles
loss of proton
wagner meerwein reaarangement
cyclization

24
Q

fates of methyl/ alpha terpinyl carion in bicyclic monoterpens

A

loss of proton forming cyclopropane ring
folding cationic side chain of methyl
wagner meerwein rearrangement

25
terpenoids derived from c5 that do not link in regular hed to tail coupling mechanism
irregular monotepenes
26
2 irregular monoterpenes
chrysanthemic acid | pyrethric acid
27
cyclopropane structures from 2 isoprene units
chrysanthemic acid
28
pyrethric acid found in nature as
pyrethrins jasmolins cinerins
29
insecticidal components in pyrethrum flowers
pyrethric acid
30
monotrpenoids with iridane skeleton
iridoids
31
contains a cyclopentane ring fused to a six membered oxygen heterocycle
iridoid
32
5 iridoids
``` nepetalactone loganin secologanin gentiopicroside valtrate ```
33
powerful attractants and stimulants for cats
nepetalactone
34
from catmint
nepetalactone
35
sci name of catmint
Nepeta cataria lamiaceae
36
representative of secoiridoid
secologanin
37
key intemediate in the biosynthesis of iridoid structures, terpenoid indole alkaloids, and tetrahydroisoquinoline alkaloids
loganin
38
found in gentian root
gentiopicroside
39
sci name of gentian root
Gentiana lutea gentianaceae
40
epoxyiridoid ester from Valeriana officinalis with sedative activity
valtrate
41
6 bicyclic monoterpenes
``` pinane fenchane carane camphane isocamphane thujane ```