mevalonate pathway 1 Flashcards

1
Q

modified terpenes by oxygen added or methyl removed or moved

A

terpenoids

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2
Q

arise from acetate via mevalonic acid

A

isoprene

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3
Q

branched 5 carbon units with 2 unsaturated bonds

A

isoprene

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4
Q

isoprene is chemically known as

A

2 methyl 1,3 butadiene

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5
Q

class name for the 1 to 8 isoprene units

A
hemiterpene-1
monoterpene-2
sesquiterpene-3
diterpene-4
sesterterpene-5
triterpene-6
tetraterpene-8
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6
Q

natural products whose structures may be divided into isoprene units

A

terpenes

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7
Q

2 active isoprene units

A

DMAPP- dimethylallyl diphosphate

IPP- isopentyl diphosphate

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8
Q

2 pathways involved in biosynthesis of isoprene

A

mevalonate

methylerythritol phosphate

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9
Q

triterpenes comes from 2

A

sesquiterpenes

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10
Q

tetraterpenes comes from 2

A

diterpene

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11
Q

3 hemiterpenes

A

IPP
DMAPP
isoprene

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12
Q

alkylating agent for meroterpenoids

A

DMAPP

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13
Q

constitutes volatile oils and used as flavoring agents

A

monoterpenes

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14
Q

used as liniments against rheumatic pain

A

camphor

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15
Q

liniments and ointments against itching

A

menthol

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16
Q

used as an aromatic bitter tonic and remedy for poor appetite

A

bitter orange peel

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17
Q

monoterpenes used as bactericidal preparations

A

thymol and carvacrol

18
Q

isomers of geranyl PP

A

linalyl PP

neryl PP

19
Q

precursors for cyclic monoterpens biosynthesis

A

neryl PP

linalyl PP

20
Q

structural forms of monoterpenes

A

acyclic
monocyclic
bicyclic

21
Q

the acyclic monotepenes are

A

hydrocarbons
aldehydes
alcohols

22
Q

formation of menthane type monoterpenes

A

monocyclic monoterpenes

23
Q

fates of methyl/ alpha terpinyl carion in monocyclic monoterpens

A

quenching ith nucleophiles
loss of proton
wagner meerwein reaarangement
cyclization

24
Q

fates of methyl/ alpha terpinyl carion in bicyclic monoterpens

A

loss of proton forming cyclopropane ring
folding cationic side chain of methyl
wagner meerwein rearrangement

25
Q

terpenoids derived from c5 that do not link in regular hed to tail coupling mechanism

A

irregular monotepenes

26
Q

2 irregular monoterpenes

A

chrysanthemic acid

pyrethric acid

27
Q

cyclopropane structures from 2 isoprene units

A

chrysanthemic acid

28
Q

pyrethric acid found in nature as

A

pyrethrins
jasmolins
cinerins

29
Q

insecticidal components in pyrethrum flowers

A

pyrethric acid

30
Q

monotrpenoids with iridane skeleton

A

iridoids

31
Q

contains a cyclopentane ring fused to a six membered oxygen heterocycle

A

iridoid

32
Q

5 iridoids

A
nepetalactone
loganin
secologanin
gentiopicroside
valtrate
33
Q

powerful attractants and stimulants for cats

A

nepetalactone

34
Q

from catmint

A

nepetalactone

35
Q

sci name of catmint

A

Nepeta cataria lamiaceae

36
Q

representative of secoiridoid

A

secologanin

37
Q

key intemediate in the biosynthesis of iridoid structures, terpenoid indole alkaloids, and tetrahydroisoquinoline alkaloids

A

loganin

38
Q

found in gentian root

A

gentiopicroside

39
Q

sci name of gentian root

A

Gentiana lutea gentianaceae

40
Q

epoxyiridoid ester from Valeriana officinalis with sedative activity

A

valtrate

41
Q

6 bicyclic monoterpenes

A
pinane
fenchane
carane
camphane
isocamphane
thujane