mevalonate pathway 1 Flashcards
modified terpenes by oxygen added or methyl removed or moved
terpenoids
arise from acetate via mevalonic acid
isoprene
branched 5 carbon units with 2 unsaturated bonds
isoprene
isoprene is chemically known as
2 methyl 1,3 butadiene
class name for the 1 to 8 isoprene units
hemiterpene-1 monoterpene-2 sesquiterpene-3 diterpene-4 sesterterpene-5 triterpene-6 tetraterpene-8
natural products whose structures may be divided into isoprene units
terpenes
2 active isoprene units
DMAPP- dimethylallyl diphosphate
IPP- isopentyl diphosphate
2 pathways involved in biosynthesis of isoprene
mevalonate
methylerythritol phosphate
triterpenes comes from 2
sesquiterpenes
tetraterpenes comes from 2
diterpene
3 hemiterpenes
IPP
DMAPP
isoprene
alkylating agent for meroterpenoids
DMAPP
constitutes volatile oils and used as flavoring agents
monoterpenes
used as liniments against rheumatic pain
camphor
liniments and ointments against itching
menthol
used as an aromatic bitter tonic and remedy for poor appetite
bitter orange peel
monoterpenes used as bactericidal preparations
thymol and carvacrol
isomers of geranyl PP
linalyl PP
neryl PP
precursors for cyclic monoterpens biosynthesis
neryl PP
linalyl PP
structural forms of monoterpenes
acyclic
monocyclic
bicyclic
the acyclic monotepenes are
hydrocarbons
aldehydes
alcohols
formation of menthane type monoterpenes
monocyclic monoterpenes
fates of methyl/ alpha terpinyl carion in monocyclic monoterpens
quenching ith nucleophiles
loss of proton
wagner meerwein reaarangement
cyclization
fates of methyl/ alpha terpinyl carion in bicyclic monoterpens
loss of proton forming cyclopropane ring
folding cationic side chain of methyl
wagner meerwein rearrangement