Metabolismo Proteínas. Flashcards

1
Q

En donde actúa la endopeptidasa

A

Con aa arompaticos

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2
Q

Pepsinógeno ⇝ Pepsina

A

Autocatálisis

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3
Q

Ph ↓ en duodeno

A

Secretina (páncreas exocrino) promueve la secreción de HCO3-

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4
Q

Colecistocinina

A

Promueve enzimas proteolíticas pancreáticas.

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5
Q

Cemaglutide

A

Análogo de GLP-1 de absorción estomacal.

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6
Q

Absorción de proteínas

A

Íleon

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7
Q

Px con cuadro agudo y repetitivo de pancreatitis.

A

Piedras en la vesícula, alcoholismo, dislipidemia ↑

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8
Q

DM 2 secundaria a pancreatitis crónica

A

No hay islotes, es insulinodependiente.

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9
Q

Sx Sullinger Ellison

A

Tumores productores de gastrina ⇝ úlceras resistentes y recurrentes.

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10
Q

Enzimas productroas de NH4+

A

TGO & TGP

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11
Q

α AA ↦ α Cetoácidos

A

Transaminación por transaminasas y aminotransferasas.

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12
Q

α Cetoglutarato ↦ Glutamato

A

Glutamato deshidrogenasa

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13
Q

Enzima que se eleva primero en el higado graso

A

γ glutamil transpeptidasa

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14
Q

Forma principal de excreción de amonio

A

UREA

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15
Q

Vit B6

A

Piridoxal.

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16
Q

Transaminasa glutámico-oxaloacética

A

Asp ➜ Oxalacetato

17
Q

Transaminasa glutámico pirúvica

A

Ala ➜ Piruvato

B1 Tiamina

18
Q

Ciclo de Felig

A

Entre músculo e hígado busca regenerar glucosa y eliminar nitrógeno.

19
Q

De donde proviene el rimer grupo amino que ingresa a ciclo de la urea

A

NH4+ Libre

20
Q

Enzima:

Carbamil P ➜ Citrulina

A

Ornitina transcarbamilasa (mitocondrias hepáticas)

21
Q

Enzima:

Cirulina ➜ [citrulín AMP] ➜ arginino succinato

A

Arginino succínico sintetasa (citosol hepático)

22
Q

Enzima:

Arginino succinato ➜ arginina

A

Arginino succinasa (citosol hepático)

23
Q

Enzima:
Arginina ➜ Ornitina
se libera Urea

A

Arginasa

24
Q

Enzima:

(NH4+) + HCO3- ➜ Carbamil P

A

Carbamil fosfato sintetasa (mitocondrias hepáticas)

25
Q

AA sustrato para Arginino succínico sintetasa

A

Oxalacetato ➜ Aspartato.