Metabolism-Drug MOAs Flashcards
Biguanides/Metformin
Decrease glucose production in the liver
Sulf./Clucatrol
Bind to beta cells to stimulate insulin production
Glinides/Prandin
Increase insulin production, short duration and given at meal times
Thaiz./Glitazones
Regulates genes involved in glucose and lipid metabolism
Dipeptidyl Peptidase IV I hibitors/Januvia
Delay incretin breakdown
Amylin Agonist/Pramlintide
Decrease postprandial BG by delaying gastric emptying and increasing full feeling
Incretin mimetics
Decrease postprandial BG by slowing gastric emptying and increasing full feeling
SLGT2 inhibitors
Inhibit glucose reabsorption in the proximal renal tubes
Alpha glucosidase/ Precose
Inhibit AG which inhibits glucose production via hydrolysis in the intestines