Metabolism-Drug MOAs Flashcards

1
Q

Biguanides/Metformin

A

Decrease glucose production in the liver

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2
Q

Sulf./Clucatrol

A

Bind to beta cells to stimulate insulin production

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3
Q

Glinides/Prandin

A

Increase insulin production, short duration and given at meal times

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4
Q

Thaiz./Glitazones

A

Regulates genes involved in glucose and lipid metabolism

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5
Q

Dipeptidyl Peptidase IV I hibitors/Januvia

A

Delay incretin breakdown

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6
Q

Amylin Agonist/Pramlintide

A

Decrease postprandial BG by delaying gastric emptying and increasing full feeling

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7
Q

Incretin mimetics

A

Decrease postprandial BG by slowing gastric emptying and increasing full feeling

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8
Q

SLGT2 inhibitors

A

Inhibit glucose reabsorption in the proximal renal tubes

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9
Q

Alpha glucosidase/ Precose

A

Inhibit AG which inhibits glucose production via hydrolysis in the intestines

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