Metabolism Flashcards

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1
Q

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A
  • The living cell is a miniature chemical factory where thousands of reactions occur.
  • The cell extracts energy stored in sugars and other fuels and applies energy to perform work.
  • Some organisms even convert energy to light, as in bioluminescence.
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2
Q

What do cells require energy to do? (T.C.P - G.M.S)

A
  • Grow & Divide (meiosis + mitosis)
  • Change shape e.g. red blood cells change shape to fit
    through tiny capillaries.
  • Move - orchestrated movement of cells in particular directions to specific locations e.g. blood clotting in wound healing.
  • Pump ions in & out (Na & K pump)
  • Transport vesicles (e.g. cell membrane proteins)
  • Synthesis macromolecules e.g. DNA, RNA, proteins complex carbohydrates.
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3
Q

What is metabolism?

A
  • The sum of all chemical reactions that take place in a living organism.
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4
Q

How do metabolic pathways begin and end? (see pics slide 4)

A
  • W/a specific molecule and ends with a product.

- Each step is catalyzed by a SPECIFIC ENZYME.

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5
Q

What are the 2 types of metabolism?

A
  • Catabolism (catabolic)

- Anabolism (anabolic)

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6
Q

What is Catabolism?

A
  • large molecules are broken down to smaller ones.
  • Exergonic - release energy (produce more energy then they consume).

E.g. The oxidation (break down) of glucose.

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7
Q

What is Anabolism?

A
  • small molecules are linked to form larger ones.
  • Endergonic (consume more energy than they produce).

E.g. The synthesis of proteins from amino acids.

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8
Q

What is ATP

A
  • adenosine triphosphate
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9
Q

What is ATP made of?

A
  • Ribose (sugar)
  • Adenine (nitrogenous base)
  • 3 Phosphate groups
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10
Q

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A
  • Triphosphate group • 3 phosphate groups • W/ high energy state
  • Adenosine :• Adenine and Ribose
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11
Q

How can the phosphate groups in ATP be broken

A
  • Through Hydrolysis
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12
Q

What happens when the phosphate terminal bond is broken?

A
  • Energy is released from ATP due to the chemical change to a state of lower free energy
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13
Q

What are the 3 types of cellular work powered by the Hydrolysis of ATP?

A
  • Chemical
  • Mechanical
  • Transport
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14
Q

Describe chemical cellular work.

powered by hydrolysis of ATP

A
  • ATP drives metabolic reactions that would not occur automatically
  • E.g. ATP phosphorylates key proteins to activate or deactivate them
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15
Q

Describe Mechanical cellular work.

powered by hydrolysis of ATP

A
  • ATP hydrolysis leads to a change in protein shape and binding ability.
  • E.g. ATP binds noncovalently to motor proteins and then in hydrolyzed to facilitate movement.
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16
Q

Describe Transport cellular work? (powered by hydrolysis of ATP)

A
  • ATP hydrolysis leads to a change in protein shape and binding ability
  • Eg. ATP phosphorylates transport protein for solute transfer in and out of the plasma membrane
17
Q

How is ATP regenerated?

A
  • By addition of a phosphate group to (ADP)

e. g. ADP + P = ATP (phosphorylation)

18
Q

Where does the energy to phosphorylate ADP come from?

A
  • Catabolic rxns in the cell.
19
Q

Read

A
  • In the cell, the energy from the exergonic (energy-releasing) reaction of ATP hydrolysis
    can be used to drive an endergonic (energy-consuming) reaction
20
Q

Read

A
  • ATP couples energy-releasing catabolic reactions to energy-requiring anabolic reactions.