Metabolic Aquired Disease

Question 1

The Wernicke-Korsakoff syndrome affects all of the following except:

A.
The hippocampus

B.
The mammillary bodies

C.
The thalamus

D.
The third nerve nucleus

Answer 1

The hippocampus;
The hippocampus is not affected in the Wernicke-Korsakoff syndrome. However, bilateral hippocampal damage can cause a memory defect (Korsakoff amnesia) similar to the WKS. The mammillary bodies, periaqueductal area, and floor of the 3rd ventricle (where the third nerve nucleus is located) are the main sites of damage.

Question 2

A 49 year old man had resection of the terminal ileum and part of the colon for Crohn’s disease. Seven years later, tingling, weakness, and spasticity of the legs develops. He should be treated with:

A.
Vitamin B12

B.
Viitamin B6

C.
Plasma exchange

D.
Vitamin B1

Answer 2

Explanation

He most likely had Vitamin B12 deficiency and subacute combined degeneration.