Menstural Cycle Flashcards
What are the 3 phases of the ovarian cycle?
Follicular Phase
Ovulation
Luteal Phase
What does the follicular phase entail?
The release of LH & FSH hormones to mature a dominant follicle.
What hormone is most dominant during the follicular phase?
Estrogen
How does a follicle become dominant?
A rise in estrogen blood level causes a negative feedback on the anterior piturary gland = stooping release of FSH.
The follicle with the most FSH receptor continues to grow and the follicles with the least FSH dies off.
What are the two cells found in a follicle that aid in folliclar maturation?
Granulosa cells: Bind FSH which release aromatase.
Theca cells: bind LH which produce androstenedione hormone
What enzyme is released from granulosa cells to convert androstenedione to 17beta estradiol?
Aromatase
At what point during the follicular phase is a the negative feedback converted into a positive feedback?
Once a follicle assumes dominance, the thea and granulosa cells continue to produce estrogen. The estrogen blood level stimulates the release of GnRH = release of FSH and LH.
When does ovulation occur?
Day 14 of the ovarian cycle
What triggers/stimulates ovulation?
During the follicular phase, follicle-stimulating hormone induces the proliferation of _____________ in the developing follicles.
granulosa cells
A burst of estradiol synthesis at the end of the follicular phase has a positive feedback effect on the secretion of follicle-stimulating hormone and luteinizing hormone, resulting in the _____________, which leads to ovulation.
luteinizing hormone surge
Ovulation occurs as a result of estrogen-induced
luteinizing hormone surge. At the endo of the follicular phase estrogen induced positive feed back and inhibin B inhibition of FSH.
The hormones produced by the ___________ during the luteal phase suppress production of follicle-stimulating hormone and luteinizing hormone.
corpus luteum
The follicular phase of the menstrual cycle is dominated by the hormone
estradiol
The rupture of the ovarian follicle occurs is called
Ovulation