Menstrual Disorders Flashcards

1
Q

What is Amenorrhea?

A

Absence of menses

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2
Q

What is primary amenorrhea?

A

Absence of menarche (first menses) by age 15 despite normal growth and secondary sexual development

Absence of menarche by age 13 in absence of normal growth or secondary sexual development

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3
Q

What is Secondary amenorrhea?

A

Absence of menses for more than 3 months (previously regular cycles), or 6 months (previously irregular cycles) in women who were previously menstruating

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4
Q

Etiologies behind Primary Amenorrhea?

A

***Chromosomal abnormality causing gonadal dysgenesis (MOST COMMON)

Hypothalamic hypogonadism

Absence of the uterus, cervix and/or vagina, mullerian agenesis

Transverse vaginal septum or imperforate hymen

Pituitary disease

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5
Q

What happens in Tuner’s syndrome?

A

(45, XO)

Results in premature depletion of oocytes and follicles
Associated with short stature, widely spaced nipples, webbed neck, and sexual infantilism

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6
Q

What causes polycystic ovary syndrome

A

usually secondary amenorrhea

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7
Q

How does Hypogonadotrophic hypogonadism cause Primary Amenorrhea?

A

Dysfunction with:

  • GnRH transport
  • GnRH pulse discharge
  • Congenital absence of GnRH
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8
Q

Disorders of HHP

A

slide 8

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9
Q

slide 9

A

9

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10
Q

How does Androgen Insensitivity Syndrome cause Primary Amenorrhea?

A

absent upper vagina, uterus and fallopian tubes on physical exam and pelvic ultrasound; high serum testosterone concentrations; and male (46,XY) karyotype

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11
Q

flow chart on slide 11

A

11

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12
Q

What is the first test you should order if someone comes in with supsected amenorrhea?

A

PREGNANCY
PRAGNANCY
PRAGNANCY

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