Infertility Flashcards
What is primary infertility
What is secondary infertility
Primary
Secondary
What is the time needed to diagnose Women 35 and over with infertility
7 months of inability to concieve
What percent is likely to conceive if sexually active in the first year?
85%
Is infertility age related?
Is it race related
Yes
No
What percent of the time is infertility related to males? Females
Males: 20%
Females: 60
15% uexplained
How can infertility be prevented?
WWE – discuss fertility, oocyte cryopreservation
Anovulation associated with weight extremes
Tobacco/recreational drug cessation
Decrease alcohol
Avoid vaginal lubricants
Avoid scrotal hyperthermia
What labs are ordered to diagnose infertility
hCG, TSH PRL Total Testosterone DHEA-S FSH LH estradiol
What lab test can you order to check ovulation in a female
Progesterone level (day 21) during Luteal phase
What is the best test to assess male infertility?
What are the 3 components of it
Semen analysis
- Count
- Motility
- Morphology
What semen count warrants an endocrinologists referral
< 5 million
Low T, High FSH, High LH indicates what in males
Primary Hpogonadism
Low T, Low FSH, Low
Secondary hypogonadism
Low LH, low sperm count, normal testosterone:
possible exogenous steroids
Treatment for infertility in young patients
Patient education–> timed intercourse
Lifestyle modifications
- BMI
- Tobacco cessation
- Diet
Medication of choice for infertility
What are its ADE
Clomiphene citrate
ADE: hot flushes, emotional lability, depression, bloating, visual changes
8% twin gestation rate
Which medication for intertility is reserved for women with hx of estrogen dependent tumors
Letrozole
What is the most common Assisted Reproductive Technologies (ART) used in infertility
Intracytoplasmic sperm injection (ICSI)
used with In vitro fertilization (IVF)
Sperm transcervically injected into uterus
How does Gamete Intrafallopian transfer procedures work
Egg and sperm placed in fallopian tube
Fertilization occurs in the body
How does the Zygote intrafallopian transfer occur?
Zygote placed into fallopian tube
Fertilization occurs in vitro
‘Natural’ implantation into uterus