menstrual disorders Flashcards

1
Q

what is secondary amenorrhea

A
  • in a woman who has previously menstruated, absence of menses for 3 months
  • in a women with irregular menses, it is 6 months absence of menses
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2
Q

what is primary amenorrhea with and w/out secondary sex characteristics

A

with: absence menstruation by age 16

w/o: absence menstruation by age 14

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3
Q

common cause of primary amenorrhea

A

pregnancy

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4
Q

women who fail to menstruate in the presence of estrogren stimuation of the endometrium…

A

are at increased risk for endometrial cancer

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5
Q

drug use, stress, big wt change, excessive exercise

A

think secondary amenorrhea

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6
Q

cause of secondary amenorrhea in a woman with nml estrogen

A

asherman syndrome(intrauterine synechiae) or PCOS

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7
Q

first line test for amenorrhea

A

B-hCG, TSH, prolactin

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8
Q

CNS tumor, stress, hyperprolactinemia, hypophysitis, sheenan syndrome, premature ovarian syndrome

A

causes of secondary amenorrhea in a hypoestrogenic women

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9
Q

what test to do determine the presence or absence of sufficient estrogen

A

progesterone challenge test

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10
Q

streak gonads, shield chest, amenorrhea, webbed neck, aortic coartatation, bicuspid aortic valve

A

turner syndrome

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11
Q

increased prolactin means what

A

inhibits the release of GnRH and thus LH and FSH; points to a pituitary pathology

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12
Q

etiology of hypogonadotrophic hypogonadism

A

hypothalmic or pituitary problem

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13
Q

etiology of hypergonadotrophic hypogonadism

A

ovaries have failed to produce estrogen

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14
Q

primary dysmenorrhea

  • caused by what
  • occurs when
A
  • painful menstruation with no pathologic abnormality
  • excess prostaglandin and leukotriene levels
  • occurs within 2 years of menarche
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15
Q

primary dysmenorrhea symptoms

A

painful contractions/cramping in lower abdomen or pelvis radiating to back/thighs, n/v, diarrhea

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16
Q

primary dysmenorrhea tx

A

NSAIDs, heat, combined OCPs, progestin IUD

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17
Q

secondary dysmenorrhea causes; age

A

endometriosis, adenomysis, fibroids, adhesions, IUD, PID;

over 25 yrs of age

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18
Q

when does primary and secondary dysmenorrhea peak

A

primary: late teens and early 20s
secondary: incidence increases with age

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19
Q

secondary dysmenorrhea symptoms

A

similar to primary but also bloating, menorrhagia, dysparenunia

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20
Q

primary and secondary dysmenorrhea related to flow

A

primary: begins or at onset of menses and lasts 1-3 days
secondary: less related to first day of flow

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21
Q

primary dysmenorrhea

  • breast development
  • pubic and axillary hair
A

yes to breast development

no pubic or axillary hair

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22
Q

imperforate hymen

A

a completely sealed hymen will prevent menstrual flow

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23
Q

gonadal agenesis or dysgenesis

A

hypoplastic dysfunctional ovaries

24
Q

turner syndrome

25
androgen insenstivity and tx
genetically male child who is phenotypically female | tx: removal of testis due to risk of testicular cancerhow
26
cervical agenesis
prevents menstrual flow
27
mullerian agenesis
uterus never develops
28
tumor of pituitary or hypothalamus
affect LH and FSH production
29
amenorrhea blood work
LH, FSH, B hCG, estrogen, prolactin, testosterone
30
amenorrhea imaging
pelvic, transvaginal, thyroid | CT/MRI hypothalamus and pituitary
31
how to define secondary amenorrhea in a pt with oligomenorrhea
12 month period without menses
32
galactorrhea
milk from breast not associated with childbirth; think secondary amenorrhea
33
sheehan syndrome
damage to pituitary secondary to ischemia during childbirth, think secondary amenorrhea
34
asherman syndrome
intrauterine adhesions
35
main difference with primary and secondary amenorrhea
primary has no pathologic findings
36
PMS occurs when during the menstrual cycle
begin 1-2 weeks before menses(luteal phase), it ends 1-2 days after the onset of menses
37
PMS and symptom free period
monthly symptom free period during follicular phase(frpm day 1 of menses to ovulation)
38
tx for mastalgia
bromocriptine
39
menopause
cessation of menses for 12 months as as result of follicular depletion average age 51 years
40
premature menopause
cessation of menses before age 40
41
age women stop menstruating
between 44 and 55
42
what happens to ovaries during menopause
they continue to produce testosterone and androstenedione; estrone is the predominant postmenopausal circulating estrogen
43
diagnostic lab for menopause
FSH greater than 30 is diagnostic
44
combine HRT increases what
risk for CV disease, breast cancer, and cognitive changes
45
contraindications to HRT
undiagnosed vaginal bleeding, acute vascular thrombosis, liver disease, hx of endometrial or breast cancer
46
follicular phase ends with what
LH surge and ovulation
47
GnRH is from where? and causes an increase in what 2 things
from anterior pituitary; increases FSH and LH
48
FSH role
causes follicle growth
49
LH role
causes egg to be released and mature, breaks down follicle walls and helps follicle to turn into corpus luteum
50
what happens 24 -36 hrs after LH surge
dominant egg is released
51
ovum lives for how long
24 hrs
52
describe temperature with ovulation
decrease with basal body temp and increase in temp
53
proliferative phase is what cycle days
7 to 14
54
days 15-28 is what 2 phases
luteal and secretory
55
progestin challenge shows withdrawal bleed
(+) anovulation due to noncyclic gonadotropin secretion. think PCOS with inc LH
56
progestin challenge shows NO withdrawal bleed
(-) uterine abnormality or estrogen deficiency