mens health in practice Flashcards

1
Q

why is the promotion of mens health so important?

A

• 2x more likely to have inadequate health
literacy
• 2x less likely to attend a GP practice
• Evidence that males socially construct health
as a feminine concern
• 2x more likely to take meds without reading
PIL
• More likely to purchase online

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2
Q

how more likely are women to go into a pharmacy than men?

A

Research suggests that men, on average, visit
the community pharmacy 4x per year, while
the average for women is 18x (NPA)

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3
Q

what are LUTS?

A

lower urinary tract symptoms

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4
Q

what are the 3 groups that LUTS are divided into?

A

Storage
Functional abnormality -Urinary urgency, frequency, nocturia, urinary incontinence,
needing to urinate just after passing urine
Voiding
Often due to detrusor underactivity –hesitancy, weak or intermittent stream,
straining, incomplete emptying, terminal dribbling
Post-micturition
Post-micturition dribble, sensation of incomplete emptying

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5
Q

what is BPH?

A

Benign prostatic hyperplasia

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6
Q

how do you investigate BPH?

A

A biopsy of the prostate shows histologic signs of hyperplastic
changes (abnormalities at the cellular level).

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7
Q

how many men with BPH have luts?

A

a quarter

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8
Q

what is the predominant problem with BPH?

A

voiding sympytoms

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9
Q

what is the most common cause of BPH?

A

voiding symptoms

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10
Q

how do you treat voiding symptoms in BPH?

A

Reassurance and lifestyle advice

• Pelvic floor training, bladder training, pads, waterproof pants etc.

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11
Q

how do you treat moderate- severe BPH sympytoms?

A

• Alpha blocker e.g. alfuzosin, doxazosin, tamsulosin or terazosin
• Review at 4-6 weeks then 6-12 months
• First dose at night (1st dose hypotension)

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12
Q

which alpha blocker for BPH can be bought OTC?

A

tamsulosin

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13
Q

what are the common side effects of alpha blocker treatment for BPH?

A

Dizziness, fatigue, postural hypotension, nasal congestion, ED,
abnormal ejaculation, drowsiness

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14
Q

what do you offer someone with an enlarged prostate?

A
  • Offer a 5-alpha reductase inhibitor
  • Dutasteride 500 micrograms daily or finasteride 5mg daily
  • Review after 3-6 months and then every 6-12 months
  • Need to be given for up to 6 months before response seen
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15
Q

what are the common side effects of 5-alpha reductase inhibitors?

A

• Sexual problems (decreasing with duration), breast

tenderness/enlargement

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16
Q

what extra precautions should be taken for those using 5-alpha reductase inhibitors?

A

• Use a condom if partner is pregnant or likely to become pregnant
• Women should not handle crushed or broken tablets or leaking
capsules if they are pregnant or planning pregnancy

17
Q

what is erectile dysfunction?

A

Erectile dysfunction is defined as the persistent inability to attain and
maintain an erection sufficient to permit satisfactory sexual
performance

18
Q

what are the common causes of ED?

A

adverse drug effects
psychological- mental health or relationship issues
physical: hormononal, anatomical ,neuro. vasculogenic

19
Q

what are the drugs that cause ED?

A
diuretics- thiazides, spironolactone
anti-hypertensives- e.g. methyldopa
fibrates- clofibrate
antipyschotics- phenothiazines
antidepressants- tricyclics
histamine-h2 antagonists
hormones and hormone modifying drugs-oestrogen
cytotocis- methotrexate
anti-arrhythmic and anti-convulsnats
20
Q

how do you diagnose ED?

A

history-
examination
investigation-10 year CVD risk
free testosterone levels

21
Q

how do you manage ED?

A

switch medication that may cause it

give phosphodiesterase-5-inhibitor

22
Q

what are the availible phosphodiesterase-5 inhibitors?

A

– Sildenafil (Viagra)
– Tadalafil(Cialis)
– verdenafil- levitra

23
Q

how do you prescribe a phosphodiesterase-5 inhibitor?

A

Prescribe the lower dose and consider titrating upwards if ineffective

24
Q

what does PDE-5 inihibitors require to work?

A

PDE-5 inhibitors are not initiators of erection but require sexual
stimulation in order to facilitate erection.

25
what would be classed as a non-responder?
A man with erectile dysfunction should receive eight doses of a PDE-5 inhibitor at a maximum dose with sexual stimulation before being classified as a non-responder.
26
what are contraindications and cautions for PDE-5 inhibitors?
• Prescribed nitrates • Vasodilation or sexual activity not recommended –recent MI, severe HF etc. • Hypotension • Recent stroke • Hepatic/renal impairment –check individual drugs
27
what are the side effects of PDE-5 inihibitors?
* Common –N&V, headache, flushing, dizziness * Visual disturbances * Prolonged and painful erection * Palpitations, tachycardia, hypersensitivity reactions, hearing loss
28
what lifestyle advise would you advise for someone with ED?
• Encourage; –Weight loss, smoking cessation, healthy diet, exercise, stress relief • Don’t –Drink more than 14 unites of alcohol per week, ? limit cycling
29
what is the dosing like for sildenafil ?
• 50mg at least 1hour before sexual activity • Longer if taken with food • Increased to a maximum dose of 100mg once daily, or reduced to 25mg once daily.
30
what is the creatinine clearance needed for sildenafil?
Creatinine clearance [CrCl] 30–80 ml/min, no dose adjustment is needed. CrCl less than 30 ml/min or impaired hepatic function, a 25mg starting dose should be considered, increased to 50mg, then 100mg based on efficacy and tolerance.
31
how is prescribing on the NHS for PDE-5 inhibitors done?
Branded products are not prescribable on an NHS prescription except: • Diabetes, MS, Parkinson's disease, poliomyelitis, prostate cancer, severe pelvic injury, single-gene neurological disease, spina bifida, or spinal cord injury. – Are receiving renal dialysis for renal failure. – Have had radical pelvic surgery, prostatectomy (including transurethral resection of the prostrate), or a kidney transplant. – Were receiving Caverject®, Erecnos®, MUSE®, Viagra®, or Viridal® at the expense of the NHS on 14September1998.
32
what class is sildenafil?
Reclassified by the MHRA from POM to P (Nov 17) • Sildenafil 50mg tablets (Viagra Connect 50mg) • Licenced over 18 years of age • Consultation with pharmacist
33
what counselling points would you give for viagra?
• Take one 50mg tablet approx. 60 minutes before sexual activity • Maximum of one per day • In order to be effective sexual stimulation is required • If taken with food it may delay the onset of activity • May effect ability to drive and use machines, due to dizziness, altered vision