Menopause

Question 1

predominating ostrgoen in premenopausal women

Answer 1

Oestradiol

Question 2

ostrogen produced by fat

Answer 2

Oestrone 10x less potest that ostrodial

Question 3

Types of HRT and when they are appropriate

Answer 3

Ostrogen only - appropriate w/ hysterectomy as emdometrial cancer not an issue

_sequential combined HR_T - menopause sx but still have periods, helps for regular bleeding. This involves cont ostrogen and courses of progesterone

continuous combimed HRT - post menopausal (1 year after last period). Involves cont progesterone and ostrogen

Question 4

cancer caused by ostrogen

Answer 4

endometrial and ovarian (if unopposed)

Question 5

cancer caused by progesterone

Answer 5

breast and cervical

Question 6

definition of menopause

Answer 6

1 year after last period

Question 7

why do we get menopause

Answer 7

You run out of eggs in your ovaries to ovulate. This leads to high levels of FSH and LH as there is not -ve feedback from eggs (oestrogen and progesterone).

Question 8

average age of menopause

Answer 8

51-52

Question 9

ago of premature menopause

Answer 9

40

Question 10

SEs of HRT

Answer 10

Headaches/migraine

Mood swings

Leg cramps

Depression

Abnormal vaginal bleeding

Fluid retention and bloating

Breast tenderness

Acne

Lower abdominal pain and backache

Dyspepsia