Meningitis

Question 1

What is the presentation of meningitis

Answer 1

acute onset of fever, severe headate with meningeal irritation

Question 2

3 causes of meningitis

Answer 2

viral, bacterial, fungal/tb

Question 3

protein state for meningitis

Answer 3

viral - normal to slightly elevated

bacterial - super elevated

fungal - elevated

Question 4

glucose state for meningitides

Answer 4

viral - normal

bacterial - down

fungal - down

Question 5

WBC’s state for meningitides

Answer 5

viral - increased lymphs

bacterial - super high PMN’s

fungal/TB - increased lymphs

Question 6

What proportion of bacterial meningitides are gram +

Answer 6

60%

Question 7

What are the 6 causes of meningitis

Answer 7

1. S. agalactia (group B strep)
2. H. influenzae B
3. s. pneumoniae
4. N. meningitidis
5. L. monocytoges
6. E. coli (but who cares?)

Question 8

What affects newborns

Answer 8

TONS of s. agalactiae

a bit L. monocytogenes

Question 9

What affects 3 mos - 3 years

Answer 9

H. influenzae B (tons)

S. pneumoniae (tons)

N. meningitidis (a bit)

Question 10

What affects 3-10

Answer 10

S. pneumoniae (tons)

N. meningiditis (tons)

H. influenzae B (a bit)

Question 11

What affects 10-25 years

Answer 11

N. meningiditis (tons)
S. pneunomiae (a bit)

Question 12

What affects >25 yrs

Answer 12

L. monocytogenes (tons)

S. pneumoniae (tons)

S. agalactiae (a bit)

Question 13

What are the pharyngeal sources of Bacterial meningitis

Answer 13

H. influenzae

s. pneumoniae
n. meningiditis

Question 14

food borne meningitis

Answer 14

listeria monocytogenes

Question 15

vertical meningitis (gi and vaginal colonization)

Answer 15

S. agalactiae

L. monocytogenes

Question 16

how do these get into the blood?

Answer 16

complement and phagocytosis escape

Question 17

what bacteria have capsule and how does evade immune response

Answer 17

strep pneumoniae, h. influenzae, and n. meningitidis

the capsule is antiphagocytic