Meningitis Flashcards

1
Q

What is meningitis

A

Infective and non-infective inflammation of the meninges

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2
Q

What are the bacterial causes of meningitis

A

S. Pneumoniae
N. Mengitidis
H. Influenzae (children)
Listeria
S. Agalectiae

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3
Q

What are the viral causes of meningitis

A
Enteroviruses
-Coxsackie A/B
-Polio
HSV2
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4
Q

What are the non-infective causes of meningitis

A
Malignancy
NSAIDs
Sarcoidosis
SLE
Behcet's
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5
Q

What are the presentations of meningitis

A
Meningism
-Headache
-Stiff neck
-Photophobia
Kerrigs Sx
Brudzinski reflex
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6
Q

What are the investigations for bacterial meningitis

A
Bloods
ABG
Blood culture
CT head
Lumbar puncture and CSF analysis
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7
Q

Why would you do a lumbar puncture (L3/4) for Meningitis

A

Check the CSF macroscopically and then send for microscopy

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8
Q

What might the CSF look like in bacterial meningitis

A
Cloudy
Neutrophilia
Culture positive
Raised Protein
Low glucose (<50%)
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9
Q

What might the CSF look like in viral meningitis

A
Clear/Turbid
Lymphocytosis
Culture negative
Normal protein
Raised glucose
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10
Q

What might the CSF look like in TB meningitis

A
Cloudy with fibrin
Lymphocytosis
High protein
Low glucose
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11
Q

What are the complications of Meningitis

A
Septic shock
DIC
Coma
Seizure
Death
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12
Q

What is Meningism

A

Headache
Stiff neck
Photophobia

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13
Q

How would bacterial meningitis be treated

A

Ceftriaxone/Cefotaxime w/ steroids

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14
Q

How would bacterial meningitis by Listeria be treated

A

Amoxicillin

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15
Q

In GP, If a patient presents with non blanching rash, what is the protocol

A

Suspect meningococcal septicemia
IM Benzylpencillin
Urgent Hospital referral

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16
Q

What are the main complications of Meningitis

A
Meningococcal septicemia (DIC)
Waterhouse Friderichsen syndrome (Adrenal insufficiency by hemorrhage)
17
Q

What is the most common bacteria causing meningitis in neonates

A

Group B Alpha (S Agalactae)
Listeria
E Coli
S Pneumonia

18
Q

What is the most common bacteria causing meningitis in infants

A

S Pneumo
N Meningitidis

N Meningitis

19
Q

What is the most common bacteria causing meningitis in adults

A

S Pneumo
N Meningitidis

N Meningitis

20
Q

What is the most common bacteria causing meningitis in elderly

A

S Pneumo
N Meningitis
Listeria (Cheese)

21
Q

Where is listeria typically found

A

Soft cheese

22
Q

What is the most common meningitis causing organism found in pregnant women

A

Gram positive Listeria

23
Q

What is Meningism

A

Haedache
Photophobia
Stiff neck

24
Q

What are the 2 main meningitis clinical signs

A

Kernig
Brudzinski

25
At what level is lumbar puncture done in meningitis
L3/L4
26
Cloudy with a fibrin web on lumbar puncture suggests what meningitis
Fungal/TB
27
In what type of meningitis is protein level found normal/ Glucose is raised on LP
Viral
28
Why is there low glucose found in lumbar puncture for bacterial and TB meningitis
Aerobic organisms use up glucose and turn the fluid cloudy
29
What are the two gram positive diplococcus most commonly found on Meningitis
S Pneumoniae S Agalectiae
30
What type of bacteria is N Meninigitidsis
Gram negative Diplococcus
31
What vaccine protects agasint N Meniningitidis
Men B/C ACWY
32
What vaccine protects against S Pneumoniae
PCV Vaccine
33
Where does S Agalacteiae colonise
Maternal flora
34
Give 4 risk factors for meningitis
Immunocompromised Crowding Extreme ages Not vaccinated