Memory Disorders Flashcards

week 4

1
Q

what would happen to memory if there was damage to the hippocampus?

A

Poor episodic memory- personal history, memory for events

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
1
Q

what would happen to memory if there was damage to the para-hippocampal cortex?

A

Poor semantic memory- general knowledge and the way the world works

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

what would happen to memory if there was damage to both the hippocampus and the para-hippocampal cortex?

A

Poor episodic/semantic memory

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

what are the causes of amnesia?

A
  • Damage to different structures of the brain causes different amnesiac syndromes
    ○ Surgery
    ○ Chronic alcohol abuse
    ○ Brain tumours
    ○ Encephalitis
    ○ Bilateral stroke
    ○ Dementia
    ○ Closed head injury
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

what are the 3 main types of amnesia?

A
  • Retrograde
    • Anterograde
  • Global
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

what is retrograde amnesia?

A
  • Poor recall for memories formed before onset of amnesia
    ○ Greater for episodic than semantic memories
    ○ Greater recall of general knowledge
    ○ Poor for personal memory recall
  • Retro= past
  • Temporal gradient (time, slope)
    ○ Before amnesia started, the percentage of recall for old memories is poorer than the memories remembered after the amnesia.
    ○ Childhood memories are in tact in comparison to memories occurring near the name of amnesia.
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

what is a temporal gradient?

A

the concept within retorgrade amnesia that sates memories before the onset of amnesia are forgotten but memories after the onset of amnesia are remembered.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

what are the 3 main explanations of the temporal gradient?

A
  1. consolodation theory
  2. semanticisation
  3. reduced learning opportunity
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

what is consolodation theory?

A

○ Acquisition= learning new memories
○ Acquisition and consolidation require different structures
○ Physiological process in the hippocampus leads to formation of long-lasting memories
○ Consolidated memories stored elsewhere, protecting them from effects of hippocampal damage
* Protects the older memories from being forgotten.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

what is semanticisation?

A

○ Episodic memories become more like semantic memories over time = protected from effects of brain-damage
○ Over time memories lose personal detail.
Become protected due to becoming more like semantic memories so are stored in a different area- protects them from brain damage.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

what is reduced learning opportunity?

A

○ Episodic memories depend on a single learning experience = reduced learning opportunity explains amnesia
§ Lived experience of an event
○ Semantic memories depend on several learning experiences
§ More robust memory trace
* All combinations contribute to the temporal gradient.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

what is anterograde amnesia?

A
  • Loss of ability to form new memories after onset of amnesia= Impaired learning after amnesia
    • Results from damage to the areas of the brain that are involved in forming new memories after the onset of amnesia.
    • Damage to the hippocampus the main cause in most instances
      Mammillary bodies and fornix also commonly involved
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

what is global amnesia?

A
  • Moderate retrograde amnesia and severe anterograde amnesia
  • A mix of both retrograde and anterograde amnesia
  • Results from lesions of structures in the medial temporal lobe, specifically the hippocampus
    ○ Hippocampus= vital for the formation of new memories.
    Patient HM
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

who is patentint HM and what is the significance with global amnesia?

A
  • Most studied amnesiac patient
  • Suffered from severe epilepsy from age of 10 years old
  • At age of 27 years, surgery to remove entire medial temporal lobe
    ○ Drastic surgery
  • Moderate retrograde and severe anterograde amnesia
    Epileptic seizures were relieved- they were lessened.
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

what is Korsakoff’s syndrome?

A
  • Also known as diencephalic amnesia
  • Most amnesic research looked at individuals who were alcoholics.
  • Vitamin B1 deficiency from chronic alcoholism
    Damage to mammillary bodies in hypothalamus
  • Memory impairment consists of the following:
    ○ Poor ability to remember events before and after onset of amnesia (retrograde/ anterograde)
    § Both forms of amnesia
    ○ Some new learning ability (e.g. motor skills)
    Slight impairment of STM (e.g. digit span)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

what are the issues with the sympotomology of Korsakoff’s syndrome?

A
  1. typically has a grdual onset= events happen before or after the onset of amnesia
  2. brain damage widespread (hippocampus and frontal)= may lead to other functional/cognitive deficits
  3. precise pattern of damage varies across patients (difficult to determine the generalisability)
  4. brain plasticity and learing od compensatpry strategies= does ot provide a direct assessment of the impact of brain damage on LTM
16
Q

what is semantic dementia?

A
  • Severe problems with semantic memory, but intact episodic memory
  • Presents itself as a language deficit.
    ○ Severe loss of information about meanings of words and concepts
    ○ Difficulty naming pictures/objects, single word comprehension, categorising, and knowing uses and features of objects.
  • Episodic memory and most executive functions (e.g. attention) reasonably intact in the early stages of semantic dementia
    ○ As it progresses, the damage to the brain widens out so overtime the semantic memories get lost.
  • Overtime, the brain regions affected spread, leads to decline in episodic memory as well as semantic memory.
    • Patients differ in terms of precise symptoms
    • Always involves degeneration of the anterior temporal lobe
      – Where semantic memories are stored
      – Perirhinal and entorhinal cortices where semantic memories formed
17
Q

what is double dissociation?

A

Amnesia and semantic dementia point to a double dissociation in long-term memory
○ identify that brain damage to one structure disrupts one cognitive process (‘X’) but not another (‘Y’)
○ Also, identify that brain damage to different structure disrupts cognitive process ‘Y’ but not ‘X’
○ E.g.: one brain area influences semantic memory but not episodic memory
Another brain area influences episodic memory but not semantic memory.

18
Q

wat is dissociation?

A

○ Identification of a brain region responsible for a cognitive process
One brain region is responsible for a brain process.

19
Q

what is single-dissociation?

A

○ Identify that brain damage to one structure disrupts one cognitive process (‘X’) but not another (‘Y’)
Only one type of memory is affected- e.g.: semantic memory affected but not episodic memory.

20
Q

what tpe of amnesia was experienced by Patient HM?

A

Global amnesia

21
Q

What type of amnesia is characterised by poor recall for memories formed before onset of amnesia?

A

retrograde amnesia

22
Q

What type of amnesia is characterised by a loss of ability to form new memories after amnesia onset?

A

Anterograde amnesia

23
Q

what is eyewitness testimony?

A
  • The accuracy of an individual’s memory is sometimes of enormous importance
    ○ You are the sole witness to a serious crime
    ○ You have to identify the perpetrator in a line-up: identification process
    ○ Your decision will be used as evidence
    Help solve a case
24
Q

how reliable is eyewitness testimony according to Wells & Olson (2003)?

A

○ “Eyewitness misidentification is the single greatest cause of wrongful convictions nationwide, playing a role in more than 75% of convictions overturned through DNA testing.” Still, the criminal justice system profoundly relies on eyewitness identification and testimony for investigating and prosecuting crimes.

25
Q

what are memory errors?

A

○ Forgetting= easier to remember recent events than distant ones
§ Recall increases and retention decreases and time increases.
○ Intrusions= Mistakes in which elements not part of original memory trace get mixed-up or intrude recall
§ Didn’t actually happen during the event.
○ Bias= Memory influenced by observer’s prior expectations
Due to individual bias

26
Q

what is forgetting?

A

Easier to remember recent events than distant ones
1. Decay
○ Memory traces fade over time
○ Less information available for retrieval as time passes
○ Temporal phasing
2. Interference
○ Similar information gets in the way of to-be-remembered information
○ 2 different types:
§ Retroactive, more recent information gets in the way of trying to recall older information
§ New memories obstruct our old memories
§ Proactive, previously learned materials get in the way of trying to recall newer materials
Old memories obstruct new memories

27
Q

what are intrusions?

A

DRM PARADIGM
* Named after Deese, Roediger and McDermott.
* Recall words semantically associated with list words (e.g., sleep), that aren’t included in list
○ Related through concept
○ Make connections between list words and this associated word, leading to memory error.
§ Like to take short cuts- leads to memory error
* Background knowledge helps to link together the list of words according to a theme, which aids recall.
When we need perform the task- doesn’t mean it is accurate.

28
Q

what is the isinformation effect?

A
  • Memories easily distorted by misleading information presented afterwards
    • Source misattribution
      ○ A memory probe (e.g., a question) activates memory traces with overlapping information
      § Probe the memory to activate memory traces.
      ○ Need to decide on the source of activated information
      § What is the source of the attribution?
      Misattribution occurs when memories from one source resemble those from another
29
Q

what did loftus and palmer study in relation to eye witness testimony?

A
  • Participants shown a film of a car accident
    • Actually travelling 12 mph.
      “How fast were the cars going when they […] into each other?”
    • Had 5 different verbs that were shown to participants.
      ○ SMASHED: Estimated speed = 41mph (due to perceived higher speed, greater contact)
      HIT: Estimated speed = 34mph (due to lower perceived speed)
    • One week later, asked (2nd condition)
      “Did you see any broken glass?”
    • SMASHED: Yes = 34% (misattribution effect)
    • HIT: Yes = 14%
      ○ Demonstrates that memory is fragile – can be distorted by changing just one word!
      § No broken glass shown in the video.
      Misattribution effect was higher for the smashed condition rather than the hit condition.
30
Q

what did Loftus study to show the effects of stress on eyewiotness testimony?

A
  • Unusual= arranged for people to have a stressful experience.
    ○ Teach them what it would be like if they were ever captured as a prisoner of war.
    ○ Have to identify who it was who conducted the investigation
    § When led to believe it was someone, often got it wrong= misinformation effect
    Shows wen you provide misinformation about an event, it can distort memory.
31
Q

what is bias?

A
  • Memory influenced by observer’s prior expectations
  • Various different forms:
    ○ Confirmation bias
    ○ Other-race effect
    ○ Unconscious transference
    ○ Age
    Weapon focus
32
Q

what is confirmation bias?

A
  • Tendency to recall information in a way that confirms pre-existing beliefs
    • Helps fill in gaps and make reasonable assumptions about what has happened
    • Schemas can lead us to form specific expectations
      ○ assume something must have happened due to our typical belief of an event.
      ○ Packets of knowledge stored in long-term memory
      ○ Cause us to reconstruct events based on…
      “what must have been true”
33
Q

what did Tuckey & Brewer (2003) study?

A
  • Participants shown film of a simulated bank robbery
    • Recalled information relevant to bank robbery schema
      ○ Robbers were male, wore disguises and demanded money
      ○ Generic information that is perceived to have occurred
    • Less likely to recall information irrelevant to schema
      Colour of getaway car- didn’t know what it was due to it not being perceived relevant.
34
Q

what is the significance of facial recognition on eyewitness testimony?

A
  • Eyewitness identification from line-ups typically depends on face recognition
    • However, often fallible- prone to error
      ○ Unconscious transference: misidentify a familiar (but innocent) face as being person responsible
      § Recognise the face from somewhere, incorrectly judge them to be responsible.
      ○ Other-race effect: recognition for same-race faces generally more accurate than other-race faces
      § Recognition for same race faces is more accurate because it is based upon a familiarity reason.
      ○ Own-age bias: more accurate when culprit is similar age to witness
      More accurate with same age due to familiarity with those who are the same age as us- more accurate recognition.
35
Q

how does anxiety and violence influence eyewitness testimony?

A
  • Anxiety and stress generally impair memory
    ○ Causes a narrowing of attention on important stimuli - tunnel vision attention.
    § Reduces ability to remember peripheral details - wider information
    • Weapon focus = attend to weapon, reducing memory for other information
      Attend to unexpected stimuli inconsistent with schema of that situation
36
Q

how do we avoid memory errors?

A

use the cognitive interview technique

37
Q

what is the cognitive interview technique?

A

○ Increases information obtained and it effective.
1. Mental reinstatement of the environment- what happened on the day, draw upon the 5 senses
2. Encourage the reporting of every detail- even things that aren’t important, can trigger another memory of the event- encourage full report
3. Describe the incident in several different orders- start in the middle or work backwards, enhance the accuracy.
4. Report the incident from different viewpoints- as the witness, victim, criminal etc.
* Stages 1 & 2 are based on the encoding specificity principle- overlap or match of context in which the event was witnessed (take them back to the place?) relive it- more likely to accurately recall info.
* Stages 3 & 4 are based on different retrieval routes
* encoding specificity princliple
* different retrieval routes

38
Q

how does speed indicate the reliability of eyewotness testimony?

A

Studies show that the longer it takes an eyewitness to decide if the perpetrator is in a line-up, the less confident they actually are about their decision
Eyewitnesses typically take several minutes to point out the perpetrator because they often feel pressured to choose the correct one