Memory And Sleep Flashcards
Hippocampus
- memory
- roll in consolidation of long-term declarative memories: transfer from short-term memory to long-term memory
- spatial working memory
Bilateral removal of the hippocampus amygdalentin medial temporal lobe
HM
- short-term memory and procedural memory were intact
- some deficits in remote long-term episodic memory
- unable to transfer new declarative information from short-term to long-term memory
Procedural memory and other implicit memories
-basal ganglia
- cerebellum
- supplementary motor area
Implicit memories
- operate on an unconscious automatic level
Damage to basal ganglia, cerebellum, supplementary motor area
- trouble learning new skills and performing previously learned skills
Amygdala
- attaching emotions to memories
- people with intact amygdalas tend to remember emotional experiences better than non-emotional ones
- people with amygdala damage have same level of recall for emotional and non-emotional experiences because emotions have not been attached to memories
Prefrontal cortex and memory
- essential for working memory aspect of short-term memory and perspective memory
Lesions in the PFC
- adversely affect event-based perspective memory more than time-based perspective memory
Event-based perspective memory
- remembering to perform intended action when a memory is triggered by a cue
Time-based perspective memory
- remembering to perform intended action at a certain time without a cue
Thalamus and mammalary bodies damage
- antero grade in retrograde amnesia
Neural mechanisms
- sea slug (apysia) research
- classical conditioning of reflexes has two effects: short-term storage of information involved in increase in the release of serotonin while long-term storage involved development of new synapses and changes in the structure of existing neurons
Long-term potentiation (LTP)
- first observed in glutamate, receptors and hippocampus
- observed in other areas of the brain including amygdala and inter-hornal cortex
- neuron as a result of rapid/ or high frequency stimulation believed to play an essential role and learning and memory formation
Synthesis of RNA
,- changes in synapses are associated with formation of long-term memories
- necessary for protein synthesis
- research found that administering a drug that inhibits RNA synthesis around a time of training prevents formation of long-term but not short-term memory
Sleep function theories
- recovery/ restoration theories
- adaptive/evolutionary theories
Recovery/ restoration theories
- the purpose of sleep is to repair damage that occurs during wakefulness
Adaptive/evolutionary theories
- sleep is related to the need to adapt to environmental threats
Example conserving energy
Stages of sleep
- all have different EEG patterns
- stage one
- stage 2
- stage 3
- stage 4
- REM sleep
Stage one sleep
- transitional stage between wakefulness and sleep
- low frequency, high aptitude alpha waves (drowsy state)
- alpha waves are then replaced by low frequency, low aptitude theta waves
Stage two sleep
- fadea waves continue but our interrupted by sleep spindles and k complexes
Sleep spindles
- sudden burst of moderately fast waves
K. Complexes
- large slow waves
Stage 3 sleep
- occurs after being asleep for 20 minutes
- low frequency, high amplitude Delta waves
- slow wave sleep
Stage 4 sleep
- Delta waves continue but are of higher amplitude
- deep sleep
REM sleep
- occurs after you’ve been asleep for 80 to 90 minutes
- EEG pattern is similar to stage one pattern
- also known as peridoxial sleep because characterized by active brain and physiological arousal while bodies major muscle groups are nearly paralyzed and persons difficult to arouse
- most dreams occur here
- dreams are more vivid, bizarre, and detailed than those in non-rem sleep
- after been asleep for 10 minutes in REM sleep you cycle through non-rim and rim sleep stages again throughout sleep period
- as night progresses duration of REM sleep increases and duration of stage 3 and 4 decrease
Sleep in newborns
- sleep longer
- spend more time in active room sleep
- begin sleep. With REM sleep that is followed by quiet non-rimmed sleep
- pattern reverses at about 3 months and four stages of sleep non- REM sleep are evident by 6 months
- total sleep time reduces from 14 to 16 hours in infancy to eight in adulthood
Sleep in older adults
- do not require less sleep
- have more difficulty falling asleep
- spend less time in deep sleep, especially stage 4
- more evenly distributed REM sleep throughout the night
- Wake up more often throughout the night
- experience in advance sleep space known as circadian phase advance= Go to sleep earlier in the evening and wake up earlier