Memory Flashcards

1
Q

Declarative memory aka

A

explicit

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2
Q

Non-declarative memory aka

A

implicit

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3
Q

Declarative memory includes

A

episodic - events

semantic - facts

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4
Q

Describe declarative memory

A

Consciously aware of it/remembering
Able to describe in words
Example: what is that

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5
Q

Non-declarative memory includes

A

procedural - motor skills you can do without thinking
conditioned
-associative (Pavlog’s dog)
-emotional

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6
Q

Working memory is

A

Combining sensory memory with stored memory to produce a new thought – a functional description of people using their stored memory.

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7
Q

How long doe short term memory last and how many items can you remember

A

lasts ~30secs-1min

7 items +/- generally, after than it’s a one in/one out scenario

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8
Q

The process of consolidation has what function

A

Making short term memories long term memories

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9
Q

What is important for consolidation

A

sleep

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10
Q

Parts of the brain involved in declarative memory

A

Input > Hippocampus > hypothalamus > thalamus > neocortex

emotion - requires amygdala

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11
Q

Parts of the brain involved in non-declarative memory

A

supplementary motor cortex (SMA)
basal ganglia
cerebellum
emotion - requires amygdala

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12
Q

Neuroplasticity is

A

the ability of neurones to makes changes to neurotransmission and synaptic structure

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13
Q

A change in neurotransmission to give a greater EPSP is called

A

long term potentiation

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14
Q

How does LTP come about

A

“neurones that fire together wire together”; if all neurones fire at the same time (or at a high frequency) they cause some change in synaptic activity which persist over time

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15
Q

Neurotransmitter critical for long term potentiation

A

glutamate

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16
Q

Receptors in long term potentiation

A

AMPA

NMDA

17
Q

NMDA receptors conduct

A

Ca

18
Q

NMDA receptors will only open when

A

only when glutamate is bound AND the membrane is depolarised enough to displace the Mg2+ block

19
Q

How does activation of NMDA receptors cause LTP (as opposed to AMPA)

A

NMDA activation > Ca entry into post-synaptic cell
> Protein kinases activated (CAMKII & PKC)
> change in gene expresion (more AMPA)
> enhance activity of AMPA (phosphorylation)

20
Q

How synaptic structure changes following LTP

A

post-synaptic dendritic spines sprout and form new synapses with axons - so 1 axon now has multiple synapses with a post-synaptic neuron

21
Q

The ion AMPA channels let through

A

Na