Memory Flashcards
What is the principle of mass of action
the proportion of damage to the brain = the proportion of function loss.
What is plasticity
it’s the ability for the brain to cope.
What was the damage to H.M
H.M had severe epilepsy. In the attempt of curing it, the MNI did a bilateral medial temporal lobectomy which caused him to not be able to store memory in the longterm.
What are the insights provided from H.M
A) hippocampus is super important for memory
B) True longterm memory is not stored in the hippocampus
The difference between learning and memory.
learning is about getting knowledge by integrating informations
memory is more of processing info which will be stored, retreived and recalled.
when the sensory info is encoded in a STM, what is the end goal? this process uses the hippocampus.
We want it to become a Long Term memory. (by doing rehearsal and consolidation.
two types of encoding
automatic and effortful..
Steps to get STM to LTM
Sensory info - brain - electrical activity - held in thalamus then STM to LTM by using LTP (longterm potentiation.
What is equipotentiality ?
the capacity of the intact brain parts to be able to do the job of the damaged ones.
What is the consequence of a high frequency stimulation?
the neurons are basically more sensitive to information and the synapses are strenghtened. (all this by Long term potentiation
The dendritic spikes are..
slight depolarization which primes the neuron to fire and removes the Mg2+ block in the receptor NMDA
what if PKM-zeta is persistingtly active after PIN-1 stops inhibiting it?
PKM-zeta is now independent of the Early LTP and can now produce proteins. Which can modulate the synapses.
