Membranes- Chapter 5 Flashcards
Phospholipid Bilayer
Two layers of phospholipids forming cell membranes.
Fluid Mosaic Model
Proteins float in lipid bilayer like boats
Transmembrane Proteins
Integral proteins spanning the lipid bilayer (embedded)
Peripheral Membrane Proteins
Proteins attached to membrane surface
Glycoproteins
Proteins with carbohydrate chains on cell surface
Glycolipids
Lipids with carbohydrate chains on cell surface
Transmission Electron Microscope
Microscope for studying membrane layers
Scanning Electron Microscope
Microscope for studying membrane surfaces
Phosphate Group
Polar, hydrophillic part of phospholipid
Fatty acids
Nonpolor, hyddrophobic components of phospholipids
Hydrogen bonding
Holds phospholipid layers together in membranes
Saturated Fatty Acids
Decrease membrane fluidity compared to unsaturated
Sterols
Lipids like cholesterol affecting membrane fluidity
Aquaporins
Proteins factilitating water transport across membranes
Passive Transport
Movement of molecules without energy input
Simple diffusion
Nonpolar molecules move across memebrane freely
Facilitated diffusion
Transport through proteins for larger molecules
Ion channels
Proteins allowing ion pasage across membranes
Osmosis
Water movement toward higher solute concentration
Hypertonic solution
Higher solute concentration
Hypotonic Solution
Lower solute concentration
Isotonic Solutions
Same concentration
Active Transport
Energy-requiring movement against concentration gradient.
Sodium-Potassium Pump
Moves Na⁺ out and K⁺ into cells.
Coupled Transport
Energy from one molecule aids another’s transport.
Endocytosis
Process of taking substances into the cell.
Exocytosis
Process of expelling substances from the cell.
Familial Hypercholesterolemia
Genetic disease causing cholesterol accumulation.
Functions of membrane proteins
- Transporters
- Enzymes
- Cell-surface receptors
- Cell-surface identity markers
- Cell-to-cell adhesion proteins
- Attachments to the cytoskeleton
b-barrel
Cylinder of B sheets in the protein secondary structure
Channel proteins
Hydrophillic when open
Carrier proteins (passive)
Bind specifically to molecules they assists
Gated channels
Open or close in response to stimuli
Carrier proteins (active)
Highly selective
Uniporters
Move one molecule at a time
Symporters
Move two molecules in same direction
Antiporters
Move two molecules in opposite directions
Symporter (Coupled)
Example: Glucose–Na⁺ symporter captures energy from Na⁺ diffusion to move glucose against its concentration gradient.
Countertransport
Moves materials in opposite directions
Phagocytosis
Cell takes in matter
Pinocytosis
Cell takes in fluid
Receptor-mediated endocytosis
Specific molecules are taken in after binding to a receptor