Membrane Transport Flashcards
Boundary that separates the living cell from its surroundings. Exhibits selective permeability. Allows some substance to cross the membrane more easily than other substance
Plasma membrane
Most abundant lipid in the plasma membrane
Phospholipids
Contain both hydrophilic and hydrophobic regions
Amphipathic molecules
can exist as a stable boundary between 2 aqueous compartments
phospholipid bilayer
A membrane that is a fluid structure with a “mosaic” of various proteins embedded in it. Proteins are not randomly distributed in the membrane
Fluid Mosaic Model
direction where lipids, and some proteins drift
laterally
determine most of the membrane’s specific functions
Membrane protein
Proteins Bound to the surface of the membrane
Peripheral protein
Proteins that Penetrate the hydrophobic core
Integral proteins
Integral proteins that span the membrane
Transmembrane protein
6 major function of membrane proteins
transport, enzymatic activity, signal transduction, cell to cell recognition, intercellular joining, attachment
Role of Membrane Carbohydrates in Cell-Cell Recognition
Cells recognize each other by binding to molecules, often containing carbohydrates, on the extracellular surface of the plasma membrane
Membrane carbohydrates may be
covalently bonded to lipids (glycolipids) or more commonly to proteins (glycoproteins)
Carbohydrates on the external side of the plasma membrane vary among species, individuals, and even cell types in an individual
Can dissolve in the lipid bilayer and pass through the membrane rapidly
Hydrophobic
Includes ions and polar molecules that do not pass the membrane easily
Hydrophilic
Allows the passage of hydrophilic substance across the membrane
Transport Proteins
With hydrophilic channel that certain molecules can use as a tunnel (transport protein)
Channel proteins
Facilitate the passage of water (under channel protein)
Aquaporins
Bind to molecules and change shape to shuttle them across the membrane, uses energy (transport protein)
Carrier proteins
Movement of molecules from an area of higher concentration to an area of lower concentration without any energy investment
The tendency for molecules to spread out evenly into the available space
Diffusion
Substances diffuse down their concentration gradient
No work must be done to move the substances down the gradient (type of transport)
Passive Transport