Membrane transport Flashcards
plasma membrane
defines all boundaries of the cell, governs interactions with other cells, controls passage of materials in/out of cell
- 98% lipids of those 75% phospholipids
- arranged in bilayer
transmembrane proteins
pass completely through the phospholipid bilayer protruding from its on both sides
-mostly glycoproteins bound tot oligosaccharides on outside
peripheral proteins
don’t protrude but adhere to either inner/outer face of membrane
functions of membrane proteins
receptors, enzymes, channels proteins, carriers, cell-identity markers, and cell adhesion molecules
receptors
surface proteins that chemical signals (that can’t enter cell) bind to
enzymes
carry out final stages of starch and protein digestion in small intestine, help produce second messengers and break down hormones/other signaling molecules who’s job is done
channel proteins
passages that allow water and hydrophilic solutes to move through membrane
leak channel
always open and allow materials to pass continually
gate channel
open/close under different circumstances
-respond to 3 stimuli
ligand gated
respond to chemical messengers
voltage gated
respond to changes in electrical potential
mechanically gated
respond to physical stress on cell
carriers
transmembrane proteins that bind to glucose, electrolytes and other solutes and transfers them to other side of membranes
cell identity markers
glycoprotein acting as a cell identity markers that enables immune system to differentiate body’s own cell from foreign cells
cell adhesion molecules
help cells adhere to one another and extracellular material
second messengers
first hormone binds to a surface receptor , receptor is linked on the intracellular side of a peripheral G protein, when activated G-protein relays signal to adenylate cyclase, adenylate cyclase removes 2 phosphate groups from ATP and converts it to cAMP the second messenger, cAMP then activated kinases which add phosphate groups to other cellular enzymes
gylcocalyx
fuzzy coat external to plasma membrane composed of carbohydrate moieties of membrane glycolipids and glycoproteins
- allows body to distinguish its own healthy cells from transplanted tissues, invading organisms and diseased cells
microvilli
extensions of plasma membrane that serve to increase a cells surface area
Brush border
dense fringe of microvilli
cilia
hairlike processes, nearly every cell has one primary one
motile cilia
less widespread but more numerous when present