Membrane Structure and Function Flashcards

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1
Q

What regions of phospholipids are hydrophobic and which are hydrophilic?

A

Hydrophobic tails inside the membrane and hydrophilic heads exposed to water on either side

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1
Q

Phospholipids are amphipathic molecules, meaning what?

A

Contains hydrophobic and hydrophilic regions

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2
Q

What is the purpose of the fluid mosaic model of membrane structure?

A

To depict the membrane as a mosaic of protein molecules bobbing in a fluid bilayer of phospholipids

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3
Q

Are proteins randomly distributed in the membrane?

A

No, they often form groups that carry out common functions

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4
Q

How does cholesterol reduce membrane fluidity at moderate temperatures?

A

By reducing phospholipid movement

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5
Q

How does cholesterol hinder solidification at low temperatures?

A

By disrupting packing

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6
Q

What are the two major types of membrane proteins?

A

Peripheral proteins, which are bound to the surface of the membrane, and Integral proteins that penetrate the hydrophobic core

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7
Q

What are transmembrane proteins?

A

Integral proteins that span the membrane

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8
Q

Hydrophobic regions of an integral protein consist of what type of amino acids?

A

Nonpolar, often coiled into α helices

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9
Q

What does the plasma membrane control?

A

The exchange of materials between the cell and its surroundings

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10
Q

Membranes exhibit selective permeability, meaning?

A

Some substances cross more easily than others

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11
Q

The fluid mosaic model explains what?

A

How membranes regulate molecular traffic across the membrane

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12
Q

What happens to the hydrophobic (nonpolar) molecules in the fluid mosaic model?

A

They dissolve in the lipid bilayer and pass through the membrane rapidly

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13
Q

What does the hydrophobic interior of the membrane do to the passage of hydrophilic (polar) molecules?

A

Blocks the passage

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14
Q

What is passive transport?

A

The diffusion of a substance across a membrane with no energy investment

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15
Q

What is diffusion?

A

The movement of particles of any substance so that they spread out evenly into the available space

16
Q

The diffusion of a substance across a biological membrane is what type of transport?

A

Passive because no additional energy is required by the cell

17
Q

What is osmosis?

A

The diffusion of free water across a selectively permeable membrane

18
Q

How do water molecules diffuse across a membrane?

A

From the region of lower solute concentration to the region of higher solute until it is equal

19
Q

What is active transport?

A

Transport requiring energy, typically in the form of ATP hydrolysis, to move substances against their concentration gradients

20
Q

How do you know if a type of transportation is active?

A

If the transport proteins move solutes against their concentration gradients

21
Q

All proteins involved in active transport are ____ proteins

A

Carrier

22
Q

What does active transport enable cells to do?

A

To maintain solute concentrations that differ from the environment

23
Q

Small molecules and water enter or leave the cell through?

A

The lipid bilayer or via transport proteins

24
Q

Large molecules, such as polysaccharides and proteins, cross the membrane in?

A

Bulk inside vesicles

25
Q

What happens during exocytosis?

A

Transport vesicles migrate to the membrane, fuse with it, and release their contents outside the cell

26
Q

What happens during endocytosis?

A

Macromolecules are taken into the cell in vesicles; The membrane forms a pocket that deepens and pinches off forming a vesicle around the material for transport

27
Q

What are the three types of endocytosis?

A
  • Phagocytosis (cellular eating)
  • Pinocytosis (cellular drinking)
  • Receptor-mediated endocytosis
28
Q
A