Membrane potentials and action potentials Flashcards

1
Q

At what voltage will the number of potassium ions leaving the cell be equal to the number entering the cell?

A

-94 millivolts

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2
Q

At rest what are nerve fibers on the outside of the cell, electropositive or electronegative?

A

Electropositive

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3
Q

At rest what are nerve fibers on the inside of the cell, electropositive or electronegative?

A

Electronegative

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4
Q

What are the 2 forces that move ions?

A

Chemical
Electric

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5
Q

Where is potassium more concentrated? (inside or outside the cell)

A

Inside

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6
Q

Where is sodium more concentrated? (inside or outside the cell)

A

Outside

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7
Q

At what voltage will the number of sodium ions leaving the cell be equal to the number entering the cell?

A

+61 millivolts

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8
Q

What can the Nernst equation do?

A

Can quantify forces acting on ions

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9
Q

What does the diffusion potential of a membrane permeable to different ions depend on? (3)

A

Polarity of the electrical charge of each ions
Permeability of the membrane to each ion
The concentration of the respective ions inside and outside of the cell membrane

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10
Q

Which equation is used to figure out the conditions of a cell membrane which has multiple ions permeable?

A

The Goldman equation

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11
Q

Why is the Nernst equation not sufficient to learn about the condition of a cell membrane?

A

As it is permeable to multiple ions, all of which need to be taken into account

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12
Q

At what voltage is all ions leaving the cell equal to all ions entering the cell? (nerve cell)

A

-70 millivolts

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13
Q

Definition of resting membrane potential

A

Estimation of voltage when forces are 0

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14
Q

Is the resting membrane potential in all cells?

A

No it varies as ion vary and their permeability varies depending on type of cell and its function

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15
Q

What causes the variation in membrane potential of cells?

A

Structure of membrane
Concentration of ions

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16
Q

What is the driving force equal to?
Vdf=?

A

Difference between the membrane potential and equilibrium potential of the ion
Vdf= Vm-Veq

17
Q

A less than 0 Vdf of cations predicts what?

A

Outward movement of ions

18
Q

A less than 0 Vdf of anions predicts what?

A

Inward movement of ions

19
Q

A more than 0 Vdf of cations predicts what?

A

Inward movement of ions

20
Q

A more than 0 Vdf of anion predicts what?

A

Outward movement of ions

21
Q

What kind of pump is the sodium potassium pump?

A

Electrogenic pump

22
Q

Which is bigger, potassium or sodium?

A

Potassium

23
Q

When are leak channels open?

A

Always

24
Q

Which is easier, for the sodium to enter the cell or potassium to leave the cell?

A

Potassium to leave the cell

25
Q

Why is the resting potential of neurons closer to the potassium membrane potential than the sodium membrane potential?

A

Because the membrane is more permeable to the potassium, it easier for it to leave the cell than it is for sodium to enter

26
Q

3 states of a voltage gated channel

A

Resten/closed
Activated/open
Inactivated

27
Q

What is conductance?

A

Current of the ions that determine a specific voltage

28
Q

What kind of feedback loop is the cycle of membrane depolarisation during the active potential?

A

Positive feedback loop

29
Q

What happens to the permeability of Na+ when a nerve fiber is increased?

A

It increases

30
Q

What happens to the potential of the heart muscle fibers before depolarisation begins?

A

Remains at a plateau

31
Q

Why does the heart muscle fibers remain at a plateau?

A

Calcium channels manage to maintain the voltage for some time

32
Q

What does rhythmical discharge cause? (3)

A

Beat of the heart
Peristalsis of intestines
Control of breathing