Membrane Physiology Review Flashcards
what are cells aurrounded by? composed of?
surrounded by plasma membrane composed of lipid bilayer
why are some tails of the lipid bilayer bend? what does this do to the membrane?
due to saturated or unsaturated FAs, gives membrane fluidity
what does the lipid bilayer do? (3)
- forms basic membrane structure
- prevent pasasge of most water-soluble substances
- largely responsible for fluidity of plasma membrane
give 6 peices besided lipid bilayer in plasma membrane
- channels
- carriers
- receptors
- docking-marker acceptors
- enzymes
- self-identity markers
what are the 3 types of membranes?
- permeable: all substances cross
- impermeable: substance can’t cross
- selectively permeable: some substance can and some substances can’t cross
what is membrane permeability influenced by? (2)
- relative solubility in lipid (uncharged or nonpolar readily permeates, charged or polar has low lipid solubility)
- size of molecule
if force is needed to produce movement across a membrane what are the two types?
active and passive
what is diffusion?
the result of molecules richoceting off each other, a steady state of equilibrium with no net mvmt, slow (slower over distance)
what are the kinds of forces that move substances acorss membranes?
gradients: chemical/concentration and electrical
what are the types of carrier mediated transport?
- facilitated diffusion (3 kinds)
- active transport
what are the 3 types of facilitated diffusion?
- uniport: one substance, one direction
- symport: 2 substances, same direction
- antiport: 2 substances, opposite directions
give example of uniport faciliated diffusion
glucose transporters
give an example of symport faciliated diffusion
pull NaCl back in inloops of Henle
give an example of antiport faciliated diffusion
H+ and Na+ in proximal convoluted tubules of kidneys
what is membrane potential?
all cells have; slightly + outside and slightly - inside
what can produce rapid, transient changes in membrane potential?
extiable tissues (nervous, muscle)
what is resting membrane potential?
constant membrane potential in excitable cells at rest and non-excitable cells
?what are 4 sources of membrane potential
- Na+: more outside the cell
- K+: more inside the cell
- A- (large, negatively charged intracellular proteins) found only inside the cell
- Cl-: more outside the cell, minor impact
describe the Na+/K+ ATPase pump
a type of facilitaed diffusion;
1. 3 Na+ from inside the cell bind to a carrier
2. the energy released from ATP changes the carrier configuration to release 3 Na+
3. carrier then binds 2 K+ from outside the cell
4. carrier configuration changes again to bring K+ inside
both Na+ and K+ move against their concentration gradients (requires energy)