Blood Vessels and Hemodynamics Flashcards
what are the 5 main types of blood vessels/
- arteries
- arterioles
- capillaries
- venules
- veins
what do arteries do?
carry blood away from the heart
what are arterioles?
smaller arteries
what are capillaries and what do they do?
thin walled, and accomplosh exchange of substances between blood and body tissues
what are venules?
small veins where capillaries reunite
what do veins do?
convey blood from tissues back to heart
what are the 3 layers of blood vessel walls? describe
- tunica interna/intima: epithelial inner lining
- tunica media: smooth muscle and elastic connective tissue
- tunica externa/adventitia: connective tissue outer covering
what accounts for the 5 types of blood vessels
modifications to the basic three layers provide the structural and functional differences in the 5 types of blood vessels
what does the tunica interna form and what is it in direct contact with?
forms the inner lining of the blood vessel; in direct contact with blood
describe the tunica interna’s contribution to the thickness of vessel walls
minimal contribution to overall vessel wall thickness
what is the innermost layer of the tunica interna? what is it continuous with?
endothelium that is continuous with the endocardial lining of the heart
what is the endothelium that is the innermost layer of the tunica interna made of?
a thin layer of flattened cells that line the inner surface of the entire cardiovascular system
what does the endothelial layer of the tunica intima do?
facilitates efficient blood flow by reducing surface friction
what is the second component of the tunica intima?
the basement membrane
what are the 3 components of the tunica intima, from innermost to outermost?
- endothelium
- basement membrane
- internal elastic lamina
what does the basement membrane of the tunica intima provide? (3)
- provides physical support base for epithelial layer
- provides framework of collagen fibers that gives basement membrane significant tensile strength
- provides resilience for strength and recoil
what does the basement membrane of the tunica intima do? (2)
- anchors endothelium to underlying connective tissue
- regulates molecular movement
describe how the basement membrane of the tunica intima regulates molecular movement
appears to play an important role in guiding cell movement during tissue repair of blood vessel walls
what is the internal elastic lamina?
the outermost part of the tunica intima
what does the internal elastic lamina of the tunica intima form?
forms the boundary between tunica interna and tunica media
what does the internal elastic lamina of the tunica intima do and how?
facilitates diffusion of materials through tunica interna to tunica media via a thin sheet of elastic fibers with window-like openings
what is the tunica media?
a muscular and connective tissue layer
which of the 3 blood vessel layers varies most among the vessel types?
tunica media
describe the tunica media in most vessels (2)
- relatively thick layer
- mainly smooth muscle cells and sustantial amounts of elastic fibers
what is the primary role of the smooth muscle cells in the tunica media?
regulate diameter of the vessel
what stimulates the smooth muscle of the tunica media to contract and what does this result in?
increased sympathetic stimulation stimulates the smooth muscle of the tunica media to contract; resulting in vasoconstriction or narrowing of the vessel lumen
along with increasing vasoconstriction, what does sympathetic stimulation result in relating to the tunica media?
also results in vasodilation and release of nitric oxide and lactic acid
what regulates the rate of blood flow through different parts of the body?
the extent of smooth muscle contractions in walls of vessels
what is crucial in regulating blood pressure relating to the tunice media?
the extent of smooth muscle contraction in a particular vessel type
what happens with the tunica media if an artery is damaged?
smooth muscle contracts (vascular spasm) to limit blood loss
what is the most variable to the tunics?
tunica media
what is the external elastic lamina?
a network of elastic fibers that separates the tunica media from the tunica externa
what is the tunica externa? what is it made of? what does it contain?
the outer covering of a blood vessel, consists of elastic and collagen fiber; contains numerous nerves
what does the tunica externa do?
helps anchor vessels to surrounding tissue
what are the vasa vasorum? (3)
- small vessels that supply blood to tissues of larger vessels
- vessels to the vessels
- can be seen on large vessels including the aorta
describe the compliance of arteries
high; walls stretch/expand easily without tearing in response to small increases in pressure
describe the tunica media of arteries
thick muscular-to-elastic tunica media
what is the largest type of artery in the body?
elastic arteries
give 3 examples of elastic arteries
- aorta
- pulmonary trunk
- branches of aorta
describe the vessel walls of arteries
relatively thin (10% of total diameter) compared with overall size of vessel
describe the tunica media of arteries
thick tunica media, dominated by elastic fibers called elastic lamellae
what do elastic arteries do?
help propel blood downward while ventricles are relaxing
when blood is ejected from the heart into arteries, what happens to accodomate the surge of blood?
artery walls stretch
as elastic fibers stretch, what happens?
they momentarily store mechanical energy are a pressure reservoir
what happens to the thing elastic fibers of arteries as they stretch to serve in the function as a pressure reservoir?
they convert stored energy into kinetic energy of blood so that blood continues to move through arteries even while ventricles are relaxed
what are elastic arteries also called?
conducting arteries
what are the 2 types of arteries?
- elastic arteries
- muscular arteries
describe muscular arteries’ tunica media compared to elastic arteries
muscular artery tunica media contains more smooth muscle and fewer elastic fibers than elastic arteries
describe the walls of muscular arteries compared to elastic arteries
muscular arteries have much thicker walls than elastic arteries
describe the vasoconstriction/vasodialtion capabilities of muscular versus elastic arteries
muscular arteries are capable of greater vasoconstriction/vasodialtion than elastic arteries
describe the range of size associated with muscular arteries
femoral is pencil sized where some are string sized that enter organs
what are muscular arteries also called?
dsitributing arteries
what percentage of total vessel diameter do muscular artery walls comprise?
25%
do muscular arteries recoil like elastic arteries? what does this mean?
do not recoil like elastic arteries, so can’t propel blood
what is primarily responsible for the function of muscular arteries?
the thick, muscular tunica media
what is vascular tone?
the ability of muscle to contract and maintain state of partial contraction
what does the realtively thick walls of muscular arterioles allow for?
not as compliant, so can use vasodilation and vasoconstriction to shift blood to where it’s needed
what does vascular tone do in muscular arteries?
stiffens vessel walls and is important in maintaining vessel pressure and efficient blood flow
what are anastomoses?
unions of branches where 2 or more arteries supply the same body region
what do anastomoses do?
provide alternate routes for blood to reach tissue
what is collateral circulation?
alternate route of blood flow to body part
do end arteries anastomose?
nope
what does obstruction of an end artery result in?
necrosis of the tissue it serves
how might blood supply also be provided (other than anastomoses)?
alternative blood routes
what are arterioles?
small arteries
what do arterioles do?
regulate blood flow into capillary network
describe the wall thickness of arterioles
1/2 vessel diameter
describe the tunica interna and elastic lamina of arterioles
think tunica intima and thin fenestrated elastic lamina
what is the terminal end of arterioles called? what does it taper toward?
metarteriole, tapers toward capillary junction