Membrane Phys Flashcards
How much of the body is total body water?
50-70%
What is the relationship of water and fat?
Inversely proportional
What are the two major fluid compartments?
ICF and ECF
What separated the ICF and ECF?
Cell membrane
What two things make up the ECF?
Plasma and Interstitial Fluid
What separates the two components of ECF?
Capillary wall
Which of the fluid compartments contains cations of K+ and Mg2+ w/proteins and organic phosphates?
ICF
Which of the fluid compartments has cations of Na+ w/ anions of Cl- and HCO3-?
ECF
Each compartment must have equal concentrations of anions and cations is what principle?
Principle of Macroscopic Electroneutrality
What two things make up the cell membrane?
Lipids and proteins
What three things make up the lipid component?
Cholesterol, phospholipids, and glycolipids
What items are lipid-soluble?
CO2, O2, fatty acids, steroid hormones
What items are water soluble?
Ions, glucose, amino acids
What five things make up the protein component of the cell membrane?
- transporters 2. cell-surface antigens 3. hormone receptors 4. enzymes 5. ion and water channels
What are the two features of phospholipids?
Phosphorylated glycerol backbone “head” and two fatty acid tails
What is the relationship of the head of the phospholipid to water?
Hydrophilic
What is the relationship of the tail of the phospholipid tails?
Hydrophobic
Due to the hydrophobic properties of the fatty acid tails, what is created to form a cell membrane?
Phospholipid bilayer
What are the two types of proteins in the cell membrane?
Integral and Peripheral
What are the characteristics of integral proteins?
Embedded and anchored to the CM by hydrophobic interactions
What are the characteristics of peripheral proteins?
Not embedded in CM or bonded but attached by electrostatic interactions
Name two examples of peripheral proteins.
Ankyrin, Cl-/HCO3- exchanger
What is created when there is a cis double bond in a phospholipid?
kink, allows for better saturation and flow
