Ion Channels Flashcards
True/False: Ion channel is an integral membrane-spanning protein that when open allows the passage of certain ions.
True
What two things do ion channels depend on?
- size of channel 2. charges lining channel
What controls ion channels ability to flow?
Gates
What is the probability of a gate being open?
Conductance
What are the three types of sensors that control gates?
Voltage-gated channels, second messenger-gated channels, ligand-gated channels
What controls a voltage-gated channels?
changes in membrane potential
What is an example of a voltage gated channel?
activation gate on Na+ channel is opened by depolarization while inactivation gate is closed by repolarization
What controls a second messenger-gated channels?
Changes in intracellular signaling molecules
Where are second messenger-gated channels located?
On the side of the ion channel
Where are ligand-gated channels located?
extracellular side of ion channel