melanoma Flashcards
1
Q
what is primary treatment for melanoma?
A
surgery
2
Q
capillary leak syndrome is most associated with ___
A
IL-2
3
Q
steroids are CI with interleukin
a. true
b. false
A
a. true
4
Q
what are the common toxicities with interferon?
A
flu-like Sx
depression
anorexia
5
Q
Which type of resistance is commonly seen with BRAF/MEK inhibitors?
A
acquired
6
Q
Ipilimumab drug class?
A
CTLA-4 inhibitor
7
Q
dose of ipilimumab?
A
3mg/kg
8
Q
nivolumab and pembrolizumab drug class?
A
PD1 inhibitors
9
Q
what is first line Tx for metastatic melanoma?
A
nivolumab + ipiliumumab
10
Q
what is the one go to for management of toxicity with checkpoint inhibitors?
A
steroids
