Lung cancer Flashcards
Which is not curable?
a. NSCLC
b. small cell
b. small cell lung cancer
What is most common type of NSCLC?
adenocarcinoma
most common in nonsmokers
Which type of NSCLC has better prognosis?
squamous cell
Which type of NSCLC has poor prognosis?
large cell
__ mutation drives cancer and allows EGFR inhibitors to be active against cancer
a. extracellular
b. intracellular
b. intracellular
ROS1 mutation is translocation
a. true
b. false
a. true
What drug is used for maintenance immunotherapy for unresectable NSCLC?
durvalumab x 12 months
2 main AEs of osimertinib?
diarrhea
rash
2 warnings with osimertinib?
qtc prolongation
cardiomyopathy
the ALK and RET inhibitor alectinib should be taken with food
a. true
b. false
a. true
What drug causes hyperkeratosis?
dabrafenib
Take dabrafenib and trametinib on ___
a. full stomach
b. empty stomach
b. empty stomach
pembrolizumab drug class?
PD1 inhibitor
concurrent chemoradiation is given with __
a. limited stage SCLC
b. extensive SCLC
a. limited stage SCLC
if relapse 6 months or more from end of extensive stage SCLC Tx use what drug?
topotecan
lurbinectedin
if > 6 months use original Tx
